New insights into the pathophysiology of dyslipidemia in type 2 diabetes

MR Taskinen, J Borén - Atherosclerosis, 2015 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
patients with type 2 diabetes, despite recent significant advances in management strategies …

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

C Lawson, JM Vicencio, DM Yellon… - Journal of …, 2016 - joe.bioscientifica.com
The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

The role of the gut microbiota in lipid and lipoprotein metabolism

Y Yu, F Raka, K Adeli - Journal of clinical medicine, 2019 - mdpi.com
Both environmental and genetic factors contribute to relative species abundance and
metabolic characteristics of the intestinal microbiota. The intestinal microbiota and …

Nervonic acid and its sphingolipids: Biological functions and potential food applications

NV Phung, F Rong, WY Xia, Y Fan, XY Li… - Critical reviews in …, 2024 - Taylor & Francis
Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …

GLP-1 and GLP-2 orchestrate intestine integrity, gut microbiota, and immune system crosstalk

N Abdalqadir, K Adeli - Microorganisms, 2022 - mdpi.com
The intestine represents the body's largest interface between internal organs and external
environments except for its nutrient and fluid absorption functions. It has the ability to sense …

New insights into the regulation of chylomicron production

S Dash, C Xiao, C Morgantini… - Annual review of …, 2015 - annualreviews.org
Dietary lipids are efficiently absorbed by the small intestine, incorporated into triglyceride-
rich lipoproteins (chylomicrons), and transported in the circulation to various tissues …

Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes

T D'Aquila, YH Hung, A Carreiro, KK Buhman - Biochimica et Biophysica …, 2016 - Elsevier
Dietary fat provides essential nutrients, contributes to energy balance, and regulates blood
lipid concentrations. These functions are important to health, but can also become …

[HTML][HTML] Regulation of chylomicron secretion: focus on post-assembly mechanisms

C Xiao, P Stahel, GF Lewis - Cellular and molecular gastroenterology and …, 2019 - Elsevier
Rapid and efficient digestion and absorption of dietary triglycerides and other lipids by the
intestine, the packaging of those lipids into lipoprotein chylomicron (CM) particles, and their …

Therapeutic potential of GLP-2 analogs in gastrointestinal disorders: current knowledge, nutritional aspects, and future perspectives

D Kounatidis, NG Vallianou, D Tsilingiris… - Current Nutrition …, 2022 - Springer
Abstract Purpose of Review Although Glucagon-like peptide (GLP)-1 receptor agonists have
been used for almost two decades in the treatment of diabetes mellitus type 2 and, lately, in …

Release of lipids stored in the intestine by glucagon-like peptide-2 involves a gut-brain neural pathway

K Mukherjee, R Wang, C Xiao - Arteriosclerosis, Thrombosis, and …, 2024 - Am Heart Assoc
BACKGROUND: The gut hormone GLP-2 (glucagon-like peptide-2) plays important roles in
lipid handling in the intestine. During postabsorptive stage, it releases preformed …