We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

Conflicting reports about whether adult hippocampal neurogenesis occurs in humans raise
questions about its significance for human health and the relevance of animal models …

Obesity affects> 600 million people worldwide, a staggering number that appears to be on
the rise. One of the lesser known consequences of obesity is its deleterious effects on …

Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …

Recent research using magnetic resonance imaging has documented changes in the adult
human brain's grey matter structure induced by alterations in experiential demands. We …

Aerobic exercise (AE) has been widely praised for its potential benefits to cognition and
overall brain and mental health. In particular, AE has a potent impact on promoting the …

The impairment of hippocampal neurogenesis at the early stages of Alzheimer's disease
(AD) is believed to support early cognitive decline. Converging studies sustain the idea that …

Adult neurogenesis, defined here as progenitor cell division generating functionally
integrated neurons in the adult brain, occurs within the hippocampus of numerous …

In the late 19th Century, Sigmund Freud described the phenomenon in which people are
unable to recall events from early childhood as infantile amnesia. Although universally …

A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is
sensitive to a variety of environmental factors. The effects of emotionally salient experiences …