The growing prevalence of MDR and XDR bacterial pathogens is posing a critical threat to
global health. Traditional antibiotic development paths have encountered significant …

Antimicrobial resistance (AMR) poses a significant threat to the health, social, environment,
and economic sectors on a global scale and requires serious attention to addressing this …

This opinion-led review paper highlights the need for novel translational research in vital-
pulp-treatment (VPT), but also discusses the challenges in translating evidence to clinics …

Multidrug-resistant bacteria, especially those that defy even last-resort antibiotics, are
causing a global health crisis fuelled by antibiotic overuse and misuse as well as the lack of …

ABSTRACT Introduction Acinetobacter baumannii complex (Abc) is currently a significant
cause of difficult-to-treat pneumonia. Due to the high prevalence rates of carbapenem-and …

The use of an exogenous pulmonary surfactant (EPS) to deliver other relevant drugs to the
lungs is a promising strategy for combined therapy. We evaluated the interaction of …

Background/Objectives: The feasibility of repurposing selective serotonin reuptake inhibitors
as adjunctive antibacterial agents is an area of current investigation. We sought to evaluate …

Drug metabolism is one of the main processes governing the pharmacokinetics and toxicity
of drugs via their chemical biotransformation and elimination. In humans, the liver, enriched …

Antibiotic resistance is a top threat to human health and a priority across the globe. This
problematic issue is accompanied by the decline of new antibiotics in the pipeline over the …

Staphylococcus aureus poses a significant threat as an opportunistic pathogen in humans,
and animal medicine, particularly in the context of hospital-acquired infections (HAIs) …