Advancing human gut microbiota research by considering gut transit time

N Procházková, G Falony, LO Dragsted, TR Licht… - Gut, 2023 - gut.bmj.com
Accumulating evidence indicates that gut transit time is a key factor in shaping the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

[HTML][HTML] The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health

JL Waters, RE Ley - BMC biology, 2019 - Springer
The Christensenellaceae, a recently described family in the phylum Firmicutes, is emerging
as an important player in human health. The relative abundance of Christensenellaceae in …

Oscillospira-a candidate for the next-generation probiotics

J Yang, Y Li, Z Wen, W Liu, L Meng, H Huang - Gut microbes, 2021 - Taylor & Francis
Oscillospira is a class of organism that often appears in high-throughput sequencing data
but has not been purely cultured and is widely present in the animal and human intestines …

[HTML][HTML] Temporal variability in quantitative human gut microbiome profiles and implications for clinical research

D Vandeputte, L De Commer, RY Tito… - Nature …, 2021 - nature.com
While clinical gut microbiota research is ever-expanding, extending reference knowledge of
healthy between-and within-subject gut microbiota variation and its drivers remains …

[HTML][HTML] Interplay between the human gut microbiome and host metabolism

A Visconti, CI Le Roy, F Rosa, N Rossi… - Nature …, 2019 - nature.com
The human gut is inhabited by a complex and metabolically active microbial ecosystem.
While many studies focused on the effect of individual microbial taxa on human health, their …

Quantitative microbiome profiling links gut community variation to microbial load

D Vandeputte, G Kathagen, K D'hoe, S Vieira-Silva… - Nature, 2017 - nature.com
Current sequencing-based analyses of faecal microbiota quantify microbial taxa and
metabolic pathways as fractions of the sample sequence library generated by each …

[HTML][HTML] The human gut microbiome: from association to modulation

TSB Schmidt, J Raes, P Bork - Cell, 2018 - cell.com
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …

The fecal metabolome as a functional readout of the gut microbiome

J Zierer, MA Jackson, G Kastenmüller, M Mangino… - Nature …, 2018 - nature.com
The human gut microbiome plays a key role in human health 1, but 16S characterization
lacks quantitative functional annotation 2. The fecal metabolome provides a functional …

The effect of host genetics on the gut microbiome

MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic… - Nature …, 2016 - nature.com
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

F Imhann, AV Vila, MJ Bonder, J Fu, D Gevers… - Gut, 2018 - gut.bmj.com
Objective Patients with IBD display substantial heterogeneity in clinical characteristics. We
hypothesise that individual differences in the complex interaction of the host genome and …