Linking gut microbiota and inflammation to obesity and insulin resistance

MJA Saad, A Santos, PO Prada - Physiology, 2016 - journals.physiology.org
Obesity and insulin resistance are the major predisposing factors to comorbidities, such as
Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative …

The role of the gut microbiota in the pathogenesis of diabetes

W Bielka, A Przezak, A Pawlik - International journal of molecular …, 2022 - mdpi.com
Diabetes mellitus is a significant clinical and therapeutic problem because it can lead to
serious long-term complications. Its pathogenesis is not fully understood, but there are …

Nitric oxide function in plant abiotic stress

NN Fancy, AK Bahlmann, GJ Loake - Plant, cell & environment, 2017 - Wiley Online Library
Abiotic stress is one of the main threats affecting crop growth and production. An
understanding of the molecular mechanisms that underpin plant responses against …

Glutamate receptor ion channels: structure, regulation, and function

SF Traynelis, LP Wollmuth, CJ McBain, FS Menniti… - Pharmacological …, 2010 - ASPET
The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Implications of glial nitric oxide in neurodegenerative diseases

JE Yuste, E Tarragon, CM Campuzano… - Frontiers in cellular …, 2015 - frontiersin.org
Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

Protein S-nitrosylation: determinants of specificity and enzymatic regulation of S-nitrosothiol-based signaling

CT Stomberski, DT Hess, JS Stamler - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide
(NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in …

Nitric oxide function in plant biology: a redox cue in deconvolution

M Yu, L Lamattina, SH Spoel, GJ Loake - New phytologist, 2014 - Wiley Online Library
Nitric oxide (NO), a gaseous, redox‐active small molecule, is gradually becoming
established as a central regulator of growth, development, immunity and environmental …

Gut microbiota, probiotics and diabetes

AC Gomes, AA Bueno, RGM de Souza, JF Mota - Nutrition journal, 2014 - Springer
Diabetes is a condition of multifactorial origin, involving several molecular mechanisms
related to the intestinal microbiota for its development. In type 2 diabetes, receptor activation …

[HTML][HTML] Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

SD Ryan, N Dolatabadi, SF Chan, X Zhang, MW Akhtar… - Cell, 2013 - cell.com
Parkinson's disease (PD) is characterized by loss of A9 dopaminergic (DA) neurons in the
substantia nigra pars compacta (SNpc). An association has been reported between PD and …

The glutamate receptor ion channels

R Dingledine, K Borges, D Bowie, SF Traynelis - Pharmacological reviews, 1999 - ASPET
The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …