The chemokine receptors CXCR1/2 and their ligand CXCL8 are essential for the activation
and trafficking of inflammatory mediators as well as tumor progression and metastasis. The …

Chemokines are a group of about 50 chemotactic cytokines crucial for the migration of
immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine …

Chronic inflammation is recognized as a threat factor for cancer progression. Release of
inflammatory molecules generates microenvironment which is highly favorable for …

During the last year, science has been focusing on the research of antivirally active
compounds overall after the SARS-CoV-2 pandemic, which caused a great amount of …

Accumulating evidence indicates that G protein-coupled receptor kinase 2 (GRK2) is a
versatile protein that acts as a signaling hub by modulating G protein-coupled receptor …

Viruses have evolved a multitude of mechanisms to combat barriers to productive infection
in the host cell. Virally-encoded miRNAs are one such means to regulate host gene …

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma
(KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 …

To date, viruses are reported to be responsible for more than 15% of all tumors worldwide.
The oncogenesis could be influenced directly by the activity of viral oncoproteins or by the …

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of several human
cancers such as Kaposi's sarcoma (KS), which represents the most common AIDS …