Rapid initiation of antiretroviral therapy for people living with HIV

A Mateo‐Urdiales, S Johnson, R Smith… - Cochrane Database …, 2019 - cochranelibrary.com
Background Despite antiretroviral therapy (ART) being widely available, HIV continues to
cause substantial illness and premature death in low‐and‐middle‐income countries. High …

Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society–USA Panel

HF Günthard, JA Aberg, JJ Eron, JF Hoy, A Telenti… - Jama, 2014 - jamanetwork.com
Importance New data and antiretroviral regimens expand treatment choices in resource-rich
settings and warrant an update of recommendations to treat adults infected with human …

A comprehensive genomics solution for HIV surveillance and clinical monitoring in low-income settings

D Bonsall, T Golubchik, M de Cesare… - Journal of clinical …, 2020 - Am Soc Microbiol
Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify
appropriate antiretroviral regimes, and characterize transmission dynamics. Despite …

All-cause mortality and serious non-AIDS events in adults with low-level human immunodeficiency virus viremia during combination antiretroviral therapy: results from …

O Elvstam, G Marrone, P Medstrand… - Clinical Infectious …, 2021 - academic.oup.com
Background The impact of low levels of human immunodeficiency virus (HIV) RNA (low-level
viremia [LLV]) during combination antiretroviral therapy (cART) on clinical outcomes is …

Point-of-care Cepheid Xpert HIV-1 viral load test in rural African communities is feasible and reliable

S Moyo, T Mohammed, KE Wirth… - Journal of clinical …, 2016 - Am Soc Microbiol
Routine monitoring of HIV-1 RNA or viral load (VL) in patients on antiretroviral therapy (ART)
is important, but there are multiple impediments to VL testing in resource-constrained …

Low-level viremia in treated HIV-1 infected patients: advances and challenges

R Bai, S Lv, H Wu, L Dai - Current HIV Research, 2022 - ingentaconnect.com
Antiretroviral therapy (ART) can effectively suppress HIV-1 replication, improving quality of
life and restoring the lifespan of persons living with HIV (PLWH) to near-normal levels …

Virological failure and all-cause mortality in HIV-positive adults with low-level viremia during antiretroviral treatment

O Elvstam, P Medstrand, A Yilmaz, PE Isberg… - PloS one, 2017 - journals.plos.org
Objective Although most HIV-infected individuals achieve undetectable viremia during
antiretroviral therapy (ART), a subset have low-level viremia (LLV) of varying duration and …

Factors associated with high-risk low-level viremia leading to virologic failure: 16-year retrospective study of a Chinese antiretroviral therapy cohort

T Zhang, H Ding, M An, X Wang, W Tian, B Zhao… - BMC Infectious …, 2020 - Springer
Background Low level viremia (LLV) often occurs during antiretroviral therapy (ART) against
HIV-1. However, whether LLV increases the risk of virologic failure (VF) is controversial …

Evaluation of the RealTime HIV-1, Xpert HIV-1, and Aptima HIV-1 Quant Dx assays in comparison to the NucliSens EasyQ HIV-1 v2. 0 assay for quantification of HIV-1 …

O Mor, Y Gozlan, M Wax, F Mileguir… - Journal of clinical …, 2015 - Am Soc Microbiol
ABSTRACT HIV-1 RNA monitoring, both before and during antiretroviral therapy, is an
integral part of HIV management worldwide. Measurements of HIV-1 viral loads are …

Factors associated with low-level viraemia and virological failure: results from the Austrian HIV cohort study

G Leierer, K Grabmeier-Pfistershammer, A Steuer… - PLoS …, 2015 - journals.plos.org
Background In human immunodeficiency virus treatment adequate virological suppression
is warranted, nevertheless for some patients it remains a challenge. We investigated factors …