In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

In recent years, cell cycle and checkpoint pathways regulation are offering new therapeutic
approaches against cancer. Isatin, is a well exploited scaffold in the anticancer domain …

Molecularly targeted therapeutic agents make up an important class of oncology drugs that
are used either alone, or in combination with classical cytotoxic agents, to combat many …

Copper (II) and zinc (II) complexes with oxindolimine ligands, obtained by a condensation
reaction between isatin (1H-indole-2, 3-dione) and 2-(2-aminoethyl) pyridine, have been …

Some copper (II) and zinc (II) complexes with oxindolimine ligands were tested regarding
their trypanocidal properties. These complexes have already shown good biological activity …

A new zinc (II) complex (1) of 5-bromo-8-hydroxyquinoline (HBrQ) was prepared and
structurally characterized using IR, ESI-MS, elemental analysis, 1H and 13C NMR, as well …

Some hydrazones and Schiff bases derived from isatin, an endogenous oxindole formed in
the metabolism of tryptophan, were obtained to investigate their effects on in vitro …

Studies on the immobilization of oxindolimine‑copper (II) or zinc (II) complexes [ML] in
synthetic beidellite (BDL) clay were developed to obtain a suitable inorganic carrier capable …

Two copper (II) complexes with tetradentate 1, 4-disubstituted-1, 2, 3-triazole ligands,[Cu L
(MeCN)](ClO4) 2 (1) and [Cu L′](ClO4) 2 (2), have been prepared and characterized by …

A new oxindolimine ligand derived from isatin (1 H-indole-2, 3-dione) and 2-
aminomethylbenzimidazole was synthesized, leading to two novel complexes after …