Diagnosis and treatment of metastatic colorectal cancer: a review

LH Biller, D Schrag - Jama, 2021 - jamanetwork.com
Importance Colorectal cancer (CRC) is the third most common cause of cancer mortality
worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new …

[HTML][HTML] Difference between left-sided and right-sided colorectal cancer: a focused review of literature

B Baran, NM Ozupek, NY Tetik, E Acar… - Gastroenterology …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer is the third most common cancer worldwide with a high mortality rate at
the advanced stages. However, colorectal cancer is not a single type of tumor; its …

[HTML][HTML] Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes

S Stintzing, S Tejpar, P Gibbs, L Thiebach… - European Journal of …, 2017 - Elsevier
Metastatic colorectal carcinoma (mCRC) is a heterogeneous disease with differing
outcomes and clinical responses and poor prognosis. CRCs can be characterised by their …

Colorectal cancer liver metastases–a population-based study on incidence, management and survival

J Engstrand, H Nilsson, C Strömberg, E Jonas… - BMC cancer, 2018 - Springer
Background Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with
liver metastases developing in 25–30% of those affected. Previous data suggest a survival …

Role of SCFAs in gut microbiome and glycolysis for colorectal cancer therapy

G Wang, Y Yu, YZ Wang, JJ Wang… - Journal of cellular …, 2019 - Wiley Online Library
Increased risk of colorectal cancer (CRC) is associated with altered intestinal microbiota as
well as short‐chain fatty acids (SCFAs) reduction of output The energy source of colon cells …

Prevalence of RAS and BRAF mutations in metastatic colorectal cancer patients by tumor sidedness: a systematic review and meta‐analysis

LC Bylsma, C Gillezeau, TA Garawin… - Cancer …, 2020 - Wiley Online Library
Studies have shown that the prevalence of RAS and BRAF mutations may differ by tumor
sidedness among metastatic colorectal cancer (mCRC) patients. Both mutation status and …

Bacterial biofilms in colorectal cancer initiation and progression

S Li, SR Konstantinov, R Smits… - Trends in molecular …, 2017 - cell.com
Intestinal microbiota have emerged as an important factor in colorectal cancer (CRC)
initiation and progression. The currently prominent view on bacterial tumorigenesis is that …

Targeting gut microbial biofilms—a key to hinder colon carcinogenesis?

SS Chew, LTH Tan, JWF Law, P Pusparajah, BH Goh… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is a global public health issue which poses a substantial
humanistic and economic burden on patients, healthcare systems and society. In recent …

Epidemiology and survival of colon cancer among Egyptians: a retrospective study

IH Metwally, M Shetiwy, AF Elalfy, A Abouzid… - … of Coloproctology (Rio …, 2018 - SciELO Brasil
Introduction: Colorectal cancer is the 4th commonest cancer in the world. Studies had shown
different tumor behavior depending on the site, pathology and stage. However the …

[HTML][HTML] From crypts to cancer: a holistic perspective on colorectal carcinogenesis and therapeutic strategies

E Gharib, GA Robichaud - International journal of molecular sciences, 2024 - mdpi.com
Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …