Peptide regulation of cell differentiation

V Khavinson, N Linkova, A Diatlova… - Stem Cell Reviews and …, 2020 - Springer
Short peptides are molecules with small molecular weight, capable of penetrating the cell
membrane and nuclear membrane for epigenetic regulation of gene expression, including …

Testing of geroprotectors in experiments on cell cultures: pros and cons

AN Khokhlov, GV Morgunova - 2017 - books.rsc.org
According to the classic definition of aging we share, it is a combination of changes in an
organism leading to an increase in the probability of its death (rate of mortality). 1–4 It should …

Peptide regulation of gene expression and protein synthesis in bronchial epithelium

VK Khavinson, SM Tendler, BF Vanyushin… - Lung, 2014 - Springer
Introduction Some studies have shown that peptides have high treatment potential due to
their biological activity, harmlessness, and tissue-specific action. Tetrapeptide Ala-Asp-Glu …

Short peptides regulate gene expression, protein synthesis and enhance life span

V Khavinson, I Popovich - 2017 - books.rsc.org
There is accumulated evidence that many of the so-called “diseases of aging”, including
cancer, are caused by dysregulated immune functions and decreased organism resistance …

Short peptides regulate gene expression

VK Khavinson, NS Lin'kova, SI Tarnovskaya - Bulletin of experimental …, 2016 - Springer
Short peptides constitute the system of signal molecules regulating the functions of the
organism at the molecular, genetic, subcellular, cellular, and tissue levels. One short peptide …

[PDF][PDF] Короткие пептиды регулируют экспрессию генов

ВХ Хавинсон, НС Линькова… - … биологии и медицины, 2016 - khavinson.info
Короткие пептиды представляют собой систему сигнальных молекул, регулирующих
функции организма на молекулярно генетическом, субклеточном, клеточном и ткане …

Short peptides and telomere length regulator hormone irisin

VK Khavinson, BI Kuznik, SI Tarnovskaya… - Bulletin of experimental …, 2016 - Springer
Irisin produced by muscles during exercise and promoting fat burning also exhibits
geroprotective effect and induces telomere elongation in normal somatic cells. Special …

GDF11 protein as a geroprotector

VK Khavinson, BI Kuznik, SI Tarnovskaya… - Biology Bulletin …, 2016 - Springer
GDF11 protein, the growth differentiation factor 11, which belongs to the TGF-β superfamily
(transforming growth factor β), shows marked geroprotective effects on the cardiovascular …

Peptides, genome, aging

VK Khavinson - Advances in Gerontology, 2014 - Springer
During investigation of the mechanism of the action of short peptides, it was established that
they regulate gene expression and protein synthesis. These peptides stimulate proliferation …

Molecular-physiological aspects of regulatory effect of peptide retinoprotectors

V Khavinson, S Trofimova, A Trofimov… - Stem Cell Reviews and …, 2019 - Springer
Retinal diseases were always difficult problem for clinical ophthalmology. Modern methods
of their treatment only decrease risk of complications, however in Russia was created better …