The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Autophagy is a self-eating process of using lysosomes to degrade macromolecular
substances (eg, proteins and organelles) that are damaged, degenerated, or aging. Lipid …

Peroxisomes are essential metabolic organelles, well known for their roles in the
metabolism of complex lipids and reactive ionic species. In the past 10 years, peroxisomes …

Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …

Abstract The Transgenic RNAi Project (TRiP), a Drosophila melanogaster functional
genomics platform at Harvard Medical School, was initiated in 2008 to generate and …

Insects are the most diverse group of animals and colonize almost all environments on our
planet. This diversity is reflected in the structure and function of the microbial communities …

In all metazoans, the intestinal tract is an essential organ to integrate nutritional signaling,
hormonal cues and immunometabolic networks. The dysregulation of intestinal epithelium …

This paper is focused on eicosanoid signaling in insect immunology. We begin with
eicosanoid biosynthesis through the actions of phospholipase A2, responsible for …

Insects live in incredibly complex environments. The intestinal epithelium of insects is in
constant contact with microorganisms, some of which are beneficial and some harmful to the …