[HTML][HTML] Association between fibrosis stage and outcomes of patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis

RS Taylor, RJ Taylor, S Bayliss, H Hagström, P Nasr… - Gastroenterology, 2020 - Elsevier
Background & Aims Biopsy-confirmed liver fibrosis is a prognostic factor for patients with
nonalcoholic fatty liver disease (NAFLD). We performed a systematic review to quantify the …

Prognostic accuracy of FIB‐4, NAFLD fibrosis score and APRI for NAFLD‐related events: a systematic review

J Lee, Y Vali, J Boursier, R Spijker… - Liver …, 2021 - Wiley Online Library
Abstract Background & Aims Fibrosis is the strongest predictor for long‐term clinical
outcomes among patients with non‐alcoholic fatty liver disease (NAFLD). There is growing …

Mortality outcomes by fibrosis stage in nonalcoholic fatty liver disease: a systematic review and meta-analysis

CH Ng, WH Lim, GEH Lim, DJH Tan, N Syn… - Clinical …, 2023 - Elsevier
Background & Aims Fibrosis is a key determinant of clinical outcomes in nonalcoholic fatty
liver disease (NAFLD), but time-dependent risk of mortality has not been reported in …

Collagen biology and non‐invasive biomarkers of liver fibrosis

MA Karsdal, SJ Daniels, S Holm Nielsen… - Liver …, 2020 - Wiley Online Library
There is an unmet need for high‐quality liquid biomarkers that can safely and reproducibly
predict the stage of fibrosis and the outcomes of chronic liver disease (CLD). The …

QUAPAS: an adaptation of the QUADAS-2 tool to assess prognostic accuracy studies

J Lee, F Mulder, M Leeflang, R Wolff… - Annals of internal …, 2022 - acpjournals.org
Whereas diagnostic tests help detect the cause of signs and symptoms, prognostic tests
assist in evaluating the probable course of the disease and future outcome. Studies to …

Noninvasive serum biomarkers for liver fibrosis in NAFLD: current and future

T Reinson, RM Buchanan… - Clinical and molecular …, 2022 - pmc.ncbi.nlm.nih.gov
In the last 20 years, noninvasive serum biomarkers to identify liver fibrosis in patients with
non-alcoholic fatty liver disease (NAFLD) have been developed, validated against liver …

[HTML][HTML] The role of fibrosis index FIB-4 in predicting liver fibrosis stage and clinical prognosis: A diagnostic or screening tool?

X Xu, L Jiang, C Wu, L Pan, Z Lou, C Peng… - Journal of the Formosan …, 2022 - Elsevier
This review evaluates the ability of the fibrosis index based on four factors (FIB-4) identifying
fibrosis stages, long-time prognosis in chronic liver disease, and short-time outcomes in …

SWOT analysis of noninvasive tests for diagnosing NAFLD with severe fibrosis: an expert review by the JANIT Forum

Y Kamada, T Nakamura, S Isobe, K Hosono… - Journal of …, 2023 - Springer
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease.
Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD can progress to liver …

Chimeric galectin-3 and collagens: Biomarkers and potential therapeutic targets in fibroproliferative diseases

P Nangia-Makker, V Hogan, V Balan, A Raz - Journal of Biological …, 2022 - ASBMB
Fibrosis, stiffening and scarring of an organ/tissue due to genetic abnormalities,
environmental factors, infection, and/or injury, is responsible for> 40% of all deaths in the …

[HTML][HTML] Liver steatosis is a strong predictor of mortality and cancer in chronic hepatitis B regardless of viral load

N Peleg, A Issachar, OS Arbib, M Cohen-Naftaly… - JHEP Reports, 2019 - Elsevier
Background & Aims Liver steatosis may occur concomitantly in patients with chronic
hepatitis B infection (CHB) and is implicated in increased morbidity and mortality. Hepatitis B …