Previous research indicates that kaempferol (Kae) promotes osteogenesis, but its underlying
mechanism of action remains unclear. The present study hypothesized that the osteogenic …

Growth-factor-free bone regeneration remains a challenge in craniofacial engineering. Here,
we engineered an osteogenic niche composed of a commercially modified alginate …

Ethnopharmacological relevance Wear particle-induced inflammatory osteoclast activation
is a master contributor to periprosthetic osteolysis, which can cause pathological bone loss …

Wear particle-induced osteoclast over-activation is a major contributor to periprosthetic
osteolysis and aseptic loosening, which can cause pathological bone loss and destruction …

Gold nanoparticles (GNPs) have been widely studied to inhibit differentiation into
osteoclasts. However, reports of the inhibitory effects of silver nanoparticles (SNPs) during …

Matrix vesicles (MVs) provide the initial site for amorphous hydroxyapatite (HA) formation
within mineralizing osteoblasts. Although Na+/Ca2+ exchanger isoform‐3 (NCX3, SLC8A3) …

Osteoimmunology mediators are critical to balance osteoblastogenesis and
osteoclastogenesis to maintain bone homeostasis. A lot of the osteoimmunology mediators …

Osteoporosis is a common skeletal disease that results in an increased risk of fractures.
However, there is no definitive cure, warranting the development of potential therapeutic …

Abstract Background Yunnan Baiyao (YNBY), a traditional Chinese medicine, is renowned
for its anti-inflammatory properties. Recent studies have suggested that YNBY plays a …

Corylin, a flavonoid isolated from the fruit of Psoralea corylifolia, has an osteogenic effect on
osteoblasts in vitro and bone micromass ex vivo. However, the effect and mechanism of …