Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies

A Aksu, S Çetinkaya, AF Yenidünya, ŞA Çetinus… - Journal of Molecular …, 2023 - Elsevier
Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …

Design, synthesis, in-vitro and in-silico studies of chromone‐isoxazoline conjugates as anti‐bacterial agents

Y Kanzouai, M Chalkha, H Hadni, M Laghmari… - Journal of Molecular …, 2023 - Elsevier
A novel series of chromone-isoxazoline conjugates was successfully synthesized by the O-
alkylation and 1, 3-dipolar cycloaddition reactions using methyl 7‑hydroxy-4H-chromone-3 …

Novel coumarin-chalcone derivatives: Synthesis, characterization, antioxidant, cyclic voltammetry, molecular modelling and biological evaluation studies as …

HÇ Onar, EM Özden, HD Taslak, İ Gülçin, A Ece… - Chemico-Biological …, 2023 - Elsevier
In this study, a total of 12 coumarin-chalcone derivatives, 6 of which are original were
synthesized. The structures of the newly synthesized compounds were elucidated by 1 H …

[HTML][HTML] Two adamantan-1-amine-based scaffolds: Synthesis, crystallographic synthons, TD/DFT calculations, in-depth molecular docking/ADME/T simulations, and …

D Majumdar, JE Philip, B Tüzün, D Sutradhar, S Roy - Results in Chemistry, 2023 - Elsevier
This work synthesized and structurally characterized the two adamantan-1-amine-based
compounds, C 10 H 18 N 2 O 3 (1) and C 21 H 23 NO (2), reacting with adamantan-1-amine …

Design, synthesis, biological evaluation and docking analysis of pyrrolidine-benzenesulfonamides as carbonic anhydrase or acetylcholinesterase inhibitors and …

S Poyraz, HA Döndaş, C Yamali… - Journal of …, 2024 - Taylor & Francis
The synthesis and biological assessment of novel multi-functionalized pyrrolidine-containing
benzenesulfonamides were reported along with their antimicrobial, antifungal, CAs …

Mathematical Modeling of the Biological Activity of a New Complex Compound Based on Palladium and Mexidol

B Tüzün, R Jafarova, I Bagirov… - Journal of …, 2023 - jbiochemtech.com
Platinum preparations are widely used in the treatment of cancer patients, as they have an
antitumor effect. However, the use of such drugs is limited due to their high toxicity. In this …

Chemical composition, antioxidant, antimicrobial and anticancer activities of endemic Cephalaria tuteliana

I Kiliccioglu, G Dulger, F Senturk, ME Bozyel… - South African Journal of …, 2024 - Elsevier
Abstract Introduction The genus Cephalaria, belonging to the Caprifoliaceae family, is a rich
source of secondary metabolites, including mainly saponins which display a variety of …

Evaluation of Biological Potency of two Endemic Species Integrated with in vitro and in silico Approches: LC–MS/MS Analysis of the Plants

D Kısa, KS Baş Topcu, B Tunçkol, N Genç… - Chemistry & …, 2024 - Wiley Online Library
In the present study, the main phytochemical components of endemic plant extracts and
inhibitory potency were screened related to different biological activities. Seven compounds …

Cephalaria tchihatchewii Boiss. Ekstrelerinin Antioksidan Aktivitesi, Metabolik Enzimler Üzerine Etkisi ve UPLC-MS/MS Analizi ile Kimyasal Karakterizasyonun …

L Güven - Journal of the Institute of Science and Technology, 2023 - dergipark.org.tr
Bu çalışma, Cephalaria tchihatchewii Boiss' in metanol ve su ekstrelerinin (MECT, WECT)
UPLC-MS/MS kullanarak kapsamlı bir kimyasal karakterizasyonunu gerçekleştirmeyi ve bu …

[PDF][PDF] A Simple and Efficient Procedure Toward 2-Thioxoquinazolin-4 (1H)-One Derivatives

F Ahmadi Shourkaei, P Rashidi Ranjbar… - Iran. J. Chem. Chem …, 2024 - ijcce.ac.ir
A facile synthetic route for constructing 2-thioxoquinazolin-4 (1H)-one derivative through
cyclization reactions using readily available starting materials 2-aminobenzoic acids …