An overview of taste-masking technologies: approaches, application, and assessment methods

S Hu, X Liu, S Zhang, D Quan - AAPS PharmSciTech, 2023 - Springer
It is well-known that plenty of active pharmaceutical ingredients (API) inherently possess an
unpleasant taste, which influences the acceptance of patients, especially children …

Direct powder extrusion 3d printing of praziquantel to overcome neglected disease formulation challenges in paediatric populations

J Boniatti, P Januskaite, LB Fonseca, AL Viçosa… - Pharmaceutics, 2021 - mdpi.com
For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a
neglected parasitic disease affecting more than 250 million people worldwide. However …

The taste-masking mechanism of chitosan at the molecular level on bitter drugs of alkaloids and flavonoid glycosides from traditional Chinese medicine

Y Xu, Q Sun, W Chen, Y Han, Y Gao, J Ye, H Wang… - Molecules, 2022 - mdpi.com
Taste masking of traditional Chinese medicines (TCMs) containing multiple bitter
components remains an important challenge. In this study, berberine (BER) in alkaloids and …

The influence of omeprazole on the dissolution processes of pH-dependent magnetic tablets assessed by pharmacomagnetography

GA Soares, DW Pires, LA Pinto, GS Rodrigues… - Pharmaceutics, 2021 - mdpi.com
Pharmacomagnetography involves the simultaneous assessment of solid dosage forms
(SDFs) in the human gastrointestinal (GI) tract and the drug plasmatic concentration, using a …

Advanced 3D and 4D microstructure study of single granule formation for pharmaceutical powders using synchrotron x‐ray imaging

S Zeinali Danalou, C Blocka, J Yang, N Zhu… - AIChE …, 2023 - Wiley Online Library
Monitoring the microstructure of the granule in the wet granulation process could play a
decisive role in obtaining high‐quality granules. Due to the complex, fast and opaque nature …

[HTML][HTML] Utilization of the Drug–Polymer Solid Dispersion Obtained by Ball Milling as a Taste Masking Method in the Development of Orodispersible Minitablets with …

M Trofimiuk, K Olechno, E Trofimiuk… - Pharmaceutics, 2024 - mdpi.com
The objective of the conducted research was to design 2 mm orodispersible minitablets of
pediatric doses of hydrocortisone (0.5 mg; 1.0 mg) with desirable pharmaceutical properties …

Effects of nano zinc oxide and nano chitosan on the taste masking paracetamol granules

T Rashidi, A Shakeri - Drug Development and Industrial Pharmacy, 2024 - Taylor & Francis
Objective The purpose of this study is to investigate the taste masking of Paracetamol
granules in the range of 250–850 µm, coated by two nanocomposites prepared from …

Effect of Molecular Weight on the Dissolution Profiles of PEG Solid Dispersions Containing Ketoprofen

HP Le Khanh, Á Haimhoffer, D Nemes, L Józsa… - Polymers, 2023 - mdpi.com
Solid dispersions are typically binary systems with a hydrophilic matrix polymer and a
lipophilic active substance. During formulation, the drug undergoes a crystalline to …

[PDF][PDF] Development a taste-masked acetaminophen solid dispersions using Eudragit® E100 polymer by solvent evaporation technique

S SHAHOUD, W ABDLWAHED… - Journal of Research in …, 2023 - researchgate.net
The bitter taste of acetaminophen greatly reduced its formulation in oral dosage forms, so
masking the taste was tested using the solid dispersion technique by Eudragit E100 and the …

Investigation of Biocompatibility of Polyethylene Glycol Derivatives and Preparation of Solid Dispersion Containing Ketoprofen

PLK Ha - 2024 - search.proquest.com
To summarize, our study investigated numerous cellular effects, in vivo toxicity, as well as
osmolality of eleven different polyethylene glycols on Caco-2 cells. Data analysis with …