Antimicrobial MOFs
Infections caused by microbes constitute a severe risk to public health and the increasing
resistance of pathogens to antibiotics has led to serious health problems in recent years …
resistance of pathogens to antibiotics has led to serious health problems in recent years …
Non-viral COVID-19 vaccine delivery systems
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …
[HTML][HTML] The storage and in-use stability of mRNA vaccines and therapeutics: not a cold case
EO Blenke, E Örnskov, C Schöneich, GA Nilsson… - Journal of …, 2023 - Elsevier
The remarkable impact of mRNA vaccines on mitigating disease and improving public
health has been amply demonstrated during the COVID-19 pandemic. Many new mRNA …
health has been amply demonstrated during the COVID-19 pandemic. Many new mRNA …
Integrating plant molecular farming and materials research for next-generation vaccines
YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need
remains for a globally available vaccine that provides longer-lasting immunity against …
remains for a globally available vaccine that provides longer-lasting immunity against …
[HTML][HTML] Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs
The outbreaks of infectious diseases that spread across countries have generally existed for
centuries. An example is the occurrence of the COVID-19 pandemic in 2020, which led to …
centuries. An example is the occurrence of the COVID-19 pandemic in 2020, which led to …
Portable, on-demand biomolecular manufacturing
Synthetic biology uses living cells as molecular foundries for the biosynthesis of drugs,
therapeutic proteins, and other commodities. However, the need for specialized equipment …
therapeutic proteins, and other commodities. However, the need for specialized equipment …
[HTML][HTML] Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2
A safe, effective, and scalable vaccine is needed to halt the ongoing SARS-CoV-2
pandemic. We describe the structure-based design of self-assembling protein nanoparticle …
pandemic. We describe the structure-based design of self-assembling protein nanoparticle …
Engineering a rugged nanoscaffold to enhance plug-and-display vaccination
Nanoscale organization is crucial to stimulating an immune response. Using self-
assembling proteins as multimerization platforms provides a safe and immunogenic system …
assembling proteins as multimerization platforms provides a safe and immunogenic system …
Mechanical release of homogenous proteins from supramolecular gels
A long-standing challenge is how to formulate proteins and vaccines to retain function
during storage and transport and to remove the burdens of cold-chain management. Any …
during storage and transport and to remove the burdens of cold-chain management. Any …