The adsorption of proteins is the initiating event in the processes occurring when blood
contacts a “foreign” surface in a medical device, leading inevitably to thrombus formation …

Biomaterials are regularly used in various types of artificial tissues and organs, such as
oxygenators, plasmapheresis equipment, hemodialysers, catheters, prostheses, stents …

Intracorporally implanted materials, such as medical devices, will provoke the body to initiate
an in-flammatory reaction. This inflammatory reaction to implanted materials is known as the …

Cell encapsulation has already shown its high potential and holds the promise for future cell
therapies to enter the clinics as a large scale treatment option for various types of diseases …

In the present study we investigate whether complement activation in blood in contact with a
model biomaterial surface (polystyrene) occurs directly on the material surface or on top of …

Fourier transform infrared spectroscopy by grazing− angle attenuated total reflection (FTIR-
GATR), ellipsometry, atomic force microscopy (AFM), UV− visible spectroscopy, and …

Self-assembled monolayers (SAMs) of alkanethiols with various terminating groups (–OH,–
CH3,–COOH) and binary mixtures of these alkanethiols were studied with respect to their …

Achieving good clinical outcomes with implanted biomaterials depends upon achieving
optimal function, both mechanical and biological, which in turn depends upon integrating …

The immune complement (IC) is a cell-free protein cascade system, and the first part of the
innate immune system to recognize foreign objects that enter the body. Elevated activation …

Heparin has traditionally been a widely used anticoagulant in blood research, but has been
shown to be inappropriate for work with the complement system because of its complement …