B cells are recognized as the main effector cells of humoral immunity which suppress tumor
progression by secreting immunoglobulins, promoting T cell response, and killing cancer …

Cancer is considered a life-threatening disease, and several factors are involved in its
development. Chemokines are small proteins that physiologically exert pivotal roles in …

Chemokines play well established roles as attractants of naïve and effector T cells. New
studies indicate that chemokines also have roles in regulating T cell differentiation. Blocking …

Natural killer (NK) cells participate in innate and adaptive immuneresponses to obligate
intracellular pathogens and malignant tumors. Twomajor NK cell subsets have been …

Chemokines, a superfamilly of small cytokine-like molecules, regulate leukocyte transport in
the body. In recent years, we have witnessed the transition of immunotherapeutic strategies …

Chemokines participate, by regulating cell trafficking and controlling angiogenesis, in the
host response during infection and inflammation. Most of these mechanisms are also …

Natural killer (NK) cells represent a major subpopulation of lymphocytes. These cells have
effector functions as they recognize and kill transformed cells as well as microbially infected …

The tumor microenvironment plays a critical role in cancer development, progression, and
control. The molecular and cellular nature of the tumor immune microenvironment influences …

A comprehensive overview of breast cancer development and progression suggests that the
process is influenced by intrinsic properties of the tumor cells, as well as by …

Many human cancers possess a complex chemokine network that may influence the extent
and phenotype of the leukocyte infiltrate, angiogenesis, tumor cell growth, survival and …