Fluorescent sensors for discriminative detection of multiple targets in pathological processes

C Yu, D Wu, L Dai, X He, JT Hou, J Shen, Z Li - Coordination Chemistry …, 2023 - Elsevier
The visualization of diseases is a crucial goal for clinicians as it aids in accurate diagnosis
and clinical surgery. In recent years, fluorescence sensors that exhibit optical changes in …

Recent progress of organic fluorescent molecules for bioimaging applications: cancer-relevant biomarkers

C Zhang, YT Sun, S Gan, A Ren, S Milaneh… - Journal of Materials …, 2023 - pubs.rsc.org
Currently, cancer threatens the quality of human life. There have been 44 drugs for various
cancer diseases among 200 drugs which were top pharmaceuticals by retail sales around …

Reversible Dual Fluorescence-Lifetime Imaging of Mitochondrial GSH and Microviscosity: Real-Time Evaluation of Ferroptosis Status

SY Wang, YC Qu, N Shao, LY Niu… - Analytical Chemistry, 2024 - ACS Publications
Ferroptosis, as a new form of regulated cell death, is implicated in various physiological and
pathological processes. Developing a single probe for an independent analysis of multiple …

Rationally Constructed De Novo Fluorescent Nanosensor for Nitric Oxide Detection and Imaging in Living Cells and Inflammatory Mice Models

Q Yang, Y Zhou, L Tan, C Xie, K Luo, X Li… - Analytical …, 2023 - ACS Publications
For the early diagnosis and effective evaluation of treatment effects of inflammation, a de
novo bioanalytical method is urgently needed to monitor the metabolite nitric oxide (NO) …

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

MC Cabello, G Chen, MJ Melville, R Osman… - Chemical …, 2024 - ACS Publications
Reactive oxygen and nitrogen species are small reactive molecules derived from elements
in the air─ oxygen and nitrogen. They are produced in biological systems to mediate …

Covalent assembly-based two-photon fluorescent probes for in situ visualizing nitroreductase activities: From cancer cells to human cancer tissues

C Xu, Z Huang, J Zhou, W Jiang, J Geng… - Biosensors and …, 2025 - Elsevier
Nitroreductase (NTR) is widely regarded as a biomarker whose enzymatic activity correlates
with the degree of hypoxia in solid malignant tumors. Herein, we utilized 2-dimethylamino-7 …

Physiological and transcriptomic changes of zebrafish (Danio rerio) in response to Isopropylate Triphenyl Phosphate (IPPP) exposure

Q Zhang, S Zheng, X Shi, C Luo, W Huang… - Environmental …, 2024 - Elsevier
Abstract Isopropylate Triphenyl Phosphate (IPPP), a novel organophosphorus flame
retardant, has become a widespread environmental pollutant. However, the toxic effects and …

Advances neurotransmitter fluorescent probe based on chemical reaction or molecular assemble and its neuroimaging

N Zhou, F Huo, C Yin - Coordination Chemistry Reviews, 2024 - Elsevier
Neurotransmitters, also known as chemical messengers, are the executors of neural signal
transduction, and abnormalities in their levels or functions are closely associated with …

Engineering organelle-specific activatable molecules for ultra-fast and reliable in situ mapping of subcellular nitric oxide

L Sun, X Wang, R Chen, X Dong, J Sun… - Journal of Materials …, 2024 - pubs.rsc.org
Nitric oxide (NO), a ubiquitous gaseous transmitter in living systems, is closely associated
with physiopathological processes in the endoplasmic reticulum and lysosomes. This free …

Construction of a Near-Infrared Fluorescent Probe for Dynamic Monitoring and Early Diagnosis of Heart Failure

L Su, J Wang, B Liu, H Liu, Q Chen, J Liu, S Li… - ACS …, 2024 - ACS Publications
Cardiac hypertrophy characterized by abnormal cardiomyocyte viscosity is a typical sign of
heart failure (HF) with vital importance for early diagnosis. However, current biochemical …