DNA-based biosensors for the biochemical analysis: A review

Y Hua, J Ma, D Li, R Wang - Biosensors, 2022 - mdpi.com
In recent years, DNA-based biosensors have shown great potential as the candidate of the
next generation biomedical detection device due to their robust chemical properties and …

Enzyme-free dynamic DNA reaction networks for on-demand bioanalysis and bioimaging

S He, J Shang, Y He, F Wang - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus The pursuit of in-depth studying the nature and law of life activity has been
dominating current research fields, ranging from fundamental biological studies to …

On‐site non‐enzymatic orthogonal activation of a catalytic DNA circuit for self‐reinforced in vivo MicroRNA imaging

S He, S Yu, R Li, Y Chen, Q Wang, Y He… - Angewandte …, 2022 - Wiley Online Library
The wide extracellular‐intracellular distribution of microRNA requires the on‐site, robust and
efficient activation of catalytic DNA circuits inside live cells. Herein, we develop an efficient …

DNA origami nano-mechanics

J Ji, D Karna, H Mao - Chemical Society Reviews, 2021 - pubs.rsc.org
Invention of DNA origami has transformed the fabrication and application of biological
nanomaterials. In this review, we discuss DNA origami nanoassemblies according to their …

Circular single-stranded DNA as switchable vector for gene expression in mammalian cells

L Tang, Z Tian, J Cheng, Y Zhang, Y Song… - Nature …, 2023 - nature.com
Synthetic gene networks in mammalian cells are currently limited to either protein-based
transcription factors or RNA-based regulators. Here, we demonstrate a regulatory approach …

Data storage based on DNA

Y Hao, Q Li, C Fan, F Wang - Small Structures, 2021 - Wiley Online Library
Recent years have witnessed the exponential growth of information, calling for the
development of new storage media. DNA provides an attractive alternative for data storage …

Recent advances in DNA nanotechnology-enabled biosensors for virus detection

L Yuwen, S Zhang, J Chao - Biosensors, 2023 - mdpi.com
Virus-related infectious diseases are serious threats to humans, which makes virus detection
of great importance. Traditional virus-detection methods usually suffer from low sensitivity …

Current understanding of biological interactions and processing of dna origami nanostructures: role of machine learning and implications in drug delivery

M Singh, D Sharma, M Garg, A Kumar, A Baliyan… - Biotechnology …, 2022 - Elsevier
DNA origami has emerged as an exciting avenue that provides a versatile two and three-
dimensional DNA-based platform for nanomedicine and drug delivery applications. Their …

Self-assembly of DNA origami for nanofabrication, biosensing, drug delivery, and computational storage

Z He, K Shi, J Li, J Chao - Iscience, 2023 - cell.com
Since the pioneering work of immobile DNA Holliday junction by Ned Seeman in the early
1980s, the past few decades have witnessed the development of DNA nanotechnology. In …

Investigation and Regulation of DNA Nanostructures on Activating cGAS‐STING Signaling

K Zou, P Zhang, Y Wang, Y Liu, B Ji, P Zhan… - Small …, 2024 - Wiley Online Library
DNA nanostructures have shown great potential in biomedical fields. However, the immune
responses, especially the activation of the cGAS‐STING signaling (A‐cGSs), induced by …