[HTML][HTML] Calcium sensing receptor signalling in physiology and cancer

SC Brennan, U Thiem, S Roth, A Aggarwal… - … et Biophysica Acta (BBA …, 2013 - Elsevier
The calcium sensing receptor (CaSR) is a class C G-protein-coupled receptor that is crucial
for the feedback regulation of extracellular free ionised calcium homeostasis. While …

The association of primary hyperparathyroidism with pancreatitis

HX Bai, M Giefer, M Patel, AI Orabi… - Journal of clinical …, 2012 - journals.lww.com
The association between primary hyperparathyroidism (PHPT) and acute or chronic
pancreatitis is controversial. For this reason, we conducted a review of the literature over the …

MECHANISMS IN ENDOCRINOLOGY: Kidney involvement in patients with primary hyperparathyroidism: an update on clinical and molecular aspects

C Verdelli, S Corbetta - European journal of endocrinology, 2017 - academic.oup.com
Primary hyperparathyroidism (PHPT) is the third most common endocrine disease. Kidney is
a target of both chronic elevated PTH and calcium in PHPT. The classic PHPT complications …

Genetics in endocrinology: gain and loss of function mutations of the calcium-sensing receptor and associated proteins: current treatment concepts

B Mayr, D Schnabel, HG Dörr… - European Journal of …, 2016 - academic.oup.com
The calcium-sensing receptor (CASR) is the main calcium sensor in the maintenance of
calcium metabolism. Mutations of the CASR, the G protein alpha 11 (GNA11) and the …

Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations

K Unger, J Wienberg, A Riches… - Endocrine-related …, 2010 - erc.bioscientifica.com
Components of the tumour microenvironment initiate and promote cancer development. In
this study, we investigated the stromal component of parathyroid neoplasia …

Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin)

W Wu, HR Zhou, JJ Pestka - Archives of toxicology, 2017 - Springer
Food contamination by the trichothecene mycotoxin deoxynivalenol (DON, vomitoxin) has
the potential to adversely affect animal and human health by suppressing food intake and …

Renal Ca2+ and Water Handling in Response to Calcium Sensing Receptor Signaling: Physiopathological Aspects and Role of CaSR-Regulated microRNAs

M Ranieri - International Journal of Molecular Sciences, 2019 - mdpi.com
Calcium (Ca2+) is a universal and vital intracellular messenger involved in a diverse range
of cellular and biological processes. Changes in the concentration of extracellular Ca2+ can …

Calcium-sensing receptor and transient receptor ankyrin-1 mediate emesis induction by deoxynivalenol (vomitoxin)

W Wu, HR Zhou, SJ Bursian, JE Link… - Toxicological …, 2017 - academic.oup.com
The common foodborne mycotoxin deoxynivalenol (DON, vomitoxin) can negatively impact
animal and human health by causing food refusal and vomiting. Gut enteroendocrine cells …

Risk of nephrolithiasis in primary hyperparathyroidism is associated with two polymorphisms of the calcium-sensing receptor gene

G Vezzoli, A Scillitani, S Corbetta, A Terranegra… - Journal of …, 2015 - Springer
Aims Two single-nucleotide polymorphisms (SNPs) at the calcium-sensing receptor (CASR)
gene were previously associated with kidney stones in patients with primary …

MEN1-related hyperparathyroidism: response to cinacalcet and its relationship with the calcium-sensing receptor gene variant Arg990Gly

M Filopanti, U Verga, F Ermetici, L Olgiati… - European journal of …, 2012 - academic.oup.com
Objective Primary hyperparathyroidism (PHPT) is a challenging problem in type 1 multiple
endocrine neoplasia (MEN1) due to the high postsurgery recurrence rate. The aim was to …