Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Background Herpesviruses represent common and significant infectious complications after
allogeneic hematopoietic cell transplantation (HCT). In the last decade, major advances in …

This study compares the outcomes before and after reducing the ATG dose from 4.5 to 2
mg/kg, in a combination of PTCy and CsA for GVHD prevention, in 250 patients treated with …

Rituximab is used to eliminate B cells as a chimeric monoclonal antibody directed against
CD20, a B-cell antigen expressed on B cells. To explore the impact of rituximab …

Letermovir (LTV) prophylaxis is effective in reducing the incidence of clinically significant
cytomegalovirus (CMV) infection (cs CMVi) after allogeneic haematopoietic stem cell …

EBV+ lymphomas constitute a significant cause of morbidity and mortality in recipients of
allogeneic hematopoietic cell (HCT) and solid organ transplants (SOT). Phase I and II trials …

Haploidentical hematopoietic cell transplantation (HaploHCT) is an alternative treatment
option for patients without a suitable 10/10 HLA matched donor. We share an updated …

Pediatric solid organ transplant is a life-saving procedure for children with end-stage organ
failure. Viral infections are a common complication following pediatric solid organ …

Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressing, life-threatening
syndrome characterized by excessive immune activation, often presenting as a complex …

Immune reconstitution (IR) after allogeneic haematopoietic cell transplantation (HCT)
represents a central determinant of the clinical post-transplant course, since the majority of …