NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

This review article intends to provide insightful advice for dissolution-dynamic nuclear
polarization in the form of a practical handbook. The goal is to aid research groups to …

NMR spectroscopy is a powerful tool to investigate molecular structure and dynamics. The
poor sensitivity of this technique, however, limits its ability to tackle questions requiring dilute …

Nuclear magnetic resonance (NMR) spectroscopy is a powerful and popular technique for
probing the molecular structures, dynamics and chemical properties. However the …

Nuclear spin hyperpolarization through signal amplification by reversible exchange
(SABRE), the non-hydrogenative version of para-hydrogen induced polarization, is …

Compared to soluble protein counterparts, the understanding of membrane protein stability,
solvent interactions, and function are not as well understood. Recent advancements in …

STING (stimulator of interferon genes) is a key regulator of innate immunity that has recently
been recognized as a promising drug target. STING is activated by cyclic dinucleotides …

Nuclear magnetic resonance (NMR) spectroscopy is a powerful method to study the
molecular structure and dynamics of materials. The inherently low sensitivity of NMR …

Hyperpolarization modalities overcome the sensitivity limitations of NMR and unlock new
applications. Signal amplification by reversible exchange (SABRE) is a particularly cheap …

We demonstrate that low-field nuclear magnetic resonance provides a means for measuring
biomacromolecular interactions without requiring a superconducting, or even a permanent …