Recent progress, challenges, and prospects of fully integrated mobile and wearable point-of-care testing systems for self-testing
The rapid growth of research in the areas of chemical and biochemical sensors, lab-on-a-
chip, mobile technology, and wearable electronics offers an unprecedented opportunity in …
chip, mobile technology, and wearable electronics offers an unprecedented opportunity in …
Point-of-care diagnostics: recent developments in a connected age
S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …
Primary human lung alveolus‐on‐a‐chip model of intravascular thrombosis for assessment of therapeutics
Pulmonary thrombosis is a significant cause of patient mortality; however, there are no
effective in vitro models of thrombi formation in human lung microvessels that could also …
effective in vitro models of thrombi formation in human lung microvessels that could also …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
H Savoji, MH Mohammadi, N Rafatian, MK Toroghi… - Biomaterials, 2019 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities
A Rana, E Westein, B Niego… - Frontiers in cardiovascular …, 2019 - frontiersin.org
Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
[HTML][HTML] Regulation of platelet activation and coagulation and its role in vascular injury and arterial thrombosis
M Tomaiuolo, LF Brass, TJ Stalker - Interventional cardiology …, 2017 - ncbi.nlm.nih.gov
Hemostasis requires the tightly regulated interaction of the coagulation system, platelets,
other blood cells and components of the vessel wall at a site of vascular injury. The …
other blood cells and components of the vessel wall at a site of vascular injury. The …
Bioprinted thrombosis-on-a-chip
Pathologic thrombosis kills more people than cancer and trauma combined; it is associated
with significant disability and morbidity, and represents a major healthcare burden. Despite …
with significant disability and morbidity, and represents a major healthcare burden. Despite …
Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer
Platelets extravasate from the circulation into tumor microenvironment, enable metastasis,
and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor …
and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor …
Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases
V Paloschi, M Sabater-Lleal… - Cardiovascular …, 2021 - academic.oup.com
The development of organs-on-chip (OoC) has revolutionized in vitro cell-culture
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
experiments by allowing a better mimicry of human physiology and pathophysiology that has …
[HTML][HTML] Advanced in vitro models of vascular biology: human induced pluripotent stem cells and organ-on-chip technology
The vascular system is one of the first to develop during embryogenesis and is essential for
all organs and tissues in our body to develop and function. It has many essential roles …
all organs and tissues in our body to develop and function. It has many essential roles …