Genome editing technologies, particularly those based on zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly …
AM Khalil - Journal of genetic engineering and biotechnology, 2020 - Elsevier
Background Development of efficient strategies has always been one of the great perspectives for biotechnologists. During the last decade, genome editing of different …
A Bhardwaj, V Nain - Journal of Genetic Engineering and Biotechnology, 2021 - Elsevier
Background Genome of an organism has always fascinated life scientists. With the discovery of restriction endonucleases, scientists were able to make targeted manipulations …
N Javaid, S Choi - Frontiers in cell and developmental biology, 2021 - frontiersin.org
The diverse applications of genetically modified cells and organisms require more precise and efficient genome-editing tool such as clustered regularly interspaced short palindromic …
This article answers two questions from the perspective of United Kingdom law and policy:(i) is health information property? and (ii) should it be? We argue that special features of health …
Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically engineered immune cells that can detect target antigens on the surface of target cells and …
Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substania nigra (SN) and is associated with progressive …
TL Roth, A Marson - Annual Review of Pathology: Mechanisms …, 2021 - annualreviews.org
Genetic diseases cause numerous complex and intractable pathologies. DNA sequences encoding each human's complexity and many disease risks are contained in the …
S Tyagi, R Kumar, A Das, SY Won, P Shukla - Journal of Biotechnology, 2020 - Elsevier
The discovery of CRISPR: Cas9 and its application as a powerful gene-editing tool has transformed the world of basic and applied science, especially the molecular biology dome …