Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases

H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang… - Science China Life …, 2020 - Springer
Cells are compartmentalized by numerous membrane-enclosed organelles and
membraneless compartments to ensure that a wide variety of cellular activities occur in a …

[HTML][HTML] Structural and functional aspects of filamins

A van der Flier, A Sonnenberg - … Et Biophysica Acta (BBA)-Molecular Cell …, 2001 - Elsevier
Filamins are a family of high molecular mass cytoskeletal proteins that organize filamentous
actin in networks and stress fibers. Over the past few years it has become clear that filamins …

Iba1 is an actin-cross-linking protein in macrophages/microglia

Y Sasaki, K Ohsawa, H Kanazawa, S Kohsaka… - … and biophysical research …, 2001 - Elsevier
Iba1 is a 17-kDa EF hand protein that is specifically expressed in macrophages/microglia
and is upregulated during the activation of these cells. When exposed to macrophage …

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

JB Gorlin, R Yamin, S Egan, M Stewart… - The Journal of cell …, 1990 - rupress.org
Actin-binding protein (ABP-280, nonmuscle filamin) is a ubiquitous dimeric actin cross-
linking phosphoprotein of peripheral cytoplasm, where it promotes orthogonal branching of …

Formation of cell-to-substrate contacts during fibroblast motility: an interference-reflexion study

CS Izzard, LR Lochner - Journal of cell science, 1980 - journals.biologists.com
The formation of close contacts and focal contacts (co. 30 nm and 10–15 nm separation
distance respectively) has been studied during the movement of chick heart fibroblasts on …

Identification of membrane proteins mediating the interaction of human platelets

D Phillips, L Jennings, H Edwards - The Journal of Cell Biology, 1980 - rupress.org
Membrane glycoproteins that mediate platelet-platelet interactions were investigated by
identifying those associated with the cytoskeletal structures from aggregated platelets. The …

Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth

J Wehland, M Osborn, K Weber - Proceedings of the …, 1977 - National Acad Sciences
Phalloidin, the toxic drug from the mushroom Amanita phalloides, was injected into the
cytoplasm of tissue culture cells and the changes in intracellular actin distribution were …

Indications for a novel muscular dystrophy pathway: γ-filamin, the muscle-specific filamin isoform, interacts with myotilin

PFM van der Ven, S Wiesner, P Salmikangas… - The Journal of cell …, 2000 - rupress.org
γ-Filamin, also called ABP-L, is a filamin isoform that is specifically expressed in striated
muscles, where it is predominantly localized in myofibrillar Z-discs. A minor fraction of the …

Characterization of muscle filamin isoforms suggests a possible role of γ‐filamin/ABP‐L in sarcomeric Z‐disc formation

PFM van der Ven, WMJ Obermann… - Cell motility and the …, 2000 - Wiley Online Library
Filamin, also called actin binding protein‐280, is a dimeric protein that cross‐links actin
filaments in the cortical cytoplasm. In addition to this ubiquitously expressed isoform (FLN1) …

Biochemistry of actomyosin-dependent cell motility (a review).

ED Korn - Proceedings of the National Academy of …, 1978 - National Acad Sciences
Actins and myosins similar to the major proteins of muscle are the major molecular
components of intricate mechanochemical systems that perform numerous vital motility and …