[HTML][HTML] MCM family in gastrointestinal cancer and other malignancies: From functional characterization to clinical implication

Y Wang, H Chen, J Zhang, ASL Cheng, J Yu… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Despite the recent advances in cancer research and treatment, gastrointestinal (GI) cancers
remain the most common deadly disease worldwide. The aberrant DNA replication serves …

Molecular insight of arsenic-induced carcinogenesis and its prevention

P Mandal - Naunyn-Schmiedeberg's archives of pharmacology, 2017 - Springer
Abstract Population of India and Bangladesh and many other parts of the world are badly
exposed to arsenic through drinking water. Due to non-availability of safe drinking water …

Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex

HY Wang, B Zhang, JN Zhou, DX Wang, YC Xu… - Cell death & …, 2019 - nature.com
Hepatocellular carcinoma (HCC) has a high mortality rate due to the lack of effective
treatments and drugs. Arsenic trioxide (ATO), which has been proved to successfully treat …

[HTML][HTML] What is the best combination treatment with transarterial chemoembolization of unresectable hepatocellular carcinoma? a systematic review and network …

H Xie, H Yu, S Tian, X Yang, X Wang, Z Yang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Objective To assess the comparative efficacy and safety of combination treatment with
transarterial chemoembolization (TACE) for patients with unresectable hepatocellular …

microRNA-539 suppresses tumor growth and tumorigenesis and overcomes arsenic trioxide resistance in hepatocellular carcinoma

C Zhu, R Zhou, Q Zhou, Y Chang, M Jiang - Life sciences, 2016 - Elsevier
Abstract Aims Dysregulation of microRNAs (miRNAs) plays a critical role in tumor growth
and progression. In this study, we sought to explore the expression and biological roles of …

lncRNA OTUD6B‐AS1 Exacerbates As2O3‐Induced Oxidative Damage in Bladder Cancer via miR‐6734‐5p‐Mediated Functional Inhibition of IDH2

Y Wang, T Yang, Y Han, Z Ren, J Zou… - … medicine and cellular …, 2020 - Wiley Online Library
Arsenic trioxide (As2O3) is a promising effective chemotherapeutic agent for cancer
treatment; however, how and through what molecular mechanisms the oxidative damage of …

Will arsenic trioxide benefit treatment of solid tumor by nano-encapsulation?

X Fu, Y Li, J Zhao, L Yu, R Luo… - Mini reviews in …, 2020 - ingentaconnect.com
Arsenic trioxide (ATO) has remarkably enhanced therapeutic efficacy in treating both newly
diagnosed and relapsed patients suffering from Acute Promyelocytic Leukemia (APL) …

Arsenic trioxide combined with transarterial chemoembolization for primary liver cancer: A meta‐analysis

XH Lv, CH Wang, Y Xie - Journal of gastroenterology and …, 2017 - Wiley Online Library
Abstract Background and Aim The benefit of combination therapy of arsenic trioxide (As2O3)
and transarterial chemoembolization (TACE) is debated. This meta‐analysis was conducted …

[HTML][HTML] Research progress in MCM family: Focus on the tumor treatment resistance

Y Tian, Y Zhou, F Chen, S Qian, X Hu, B Zhang… - Biomedicine & …, 2024 - Elsevier
Malignant tumors constitute a significant category of diseases posing a severe threat to
human survival and health, thereby representing one of the most challenging and pressing …

Arsenic trioxide combined with transarterial chemoembolization for unresectable primary hepatic carcinoma: a systematic review and meta-analysis

P Song, Y Hai, W Ma, L Zhao, X Wang, Q Xie, Y Li… - Medicine, 2018 - journals.lww.com
Background: Primary hepatic carcinoma (PHC) is the third commonest leading to cancer
death around the world, and transarterial chemoembolization (TACE) has been proposed as …