Iron overload disorders lead to excess iron deposition in the body, which can occur as a
result of genetic or secondary causes. Genetic iron overload, referred to as hereditary …

Importance Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …

Iron is essential for many physiological processes, and the dysregulation of its metabolism is
implicated in the pathogenesis of various diseases. Recent advances in iron metabolism …

Objectives: To evaluate any association between the frequency of hereditary
hemochromatosis (HFE) gene mutation (H63D and C282Y) and iron overload in beta …

Abstract The Eastern Mediterranean is among the regions where sickle cell disease (SCD)
is common. The morbidity and mortality of this disease can be postponed to adulthood …

Hereditary hemochromatosis (HH) is a recessive disease, associated with an elevated level
of iron in the parenchymal cells of primary organs. The isolates from infected individuals …

Emoglobinopatie: caratterizzazione genetica molecolare e flussi migratori in una regione
non endemica. Le emoglobinopatie sono le malattie monogeniche più comuni al mondo …

This case report describes a newborn girl born with non-immune hydrops fetalis with
bicytopenia and elevated iron indexes. A genetic study which was done revealed a positive …