Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

Advances in biomaterials and technologies for vascular embolization

J Hu, H Albadawi, BW Chong, AR Deipolyi… - Advanced …, 2019 - Wiley Online Library
Minimally invasive transcatheter embolization is a common nonsurgical procedure in
interventional radiology used for the deliberate occlusion of blood vessels for the treatment …

Anomalous properties of cyclodextrins and their complexes in aqueous solutions

T Loftsson, HH Sigurdsson, P Jansook - Materials, 2023 - mdpi.com
Cyclodextrins (CDs) are cyclic oligosaccharides that emerged as industrial excipients in the
early 1970s and are currently found in at least 130 marketed pharmaceutical products, in …

Drug‐Primed Self‐Assembly of Platinum‐Single‐Atom Nanozyme to Regulate Cellular Redox Homeostasis Against Cancer

L Zhang, Q Dong, Y Hao, Z Wang, W Dong… - Advanced …, 2023 - Wiley Online Library
Single‐atom nanozymes (SAzymes) with high catalytic activity exhibit the potential to
disequilibrate the reactive oxygen metabolic balance in the tumor microenvironment (TME) …

Self-association of cyclodextrins and cyclodextrin complexes in aqueous solutions

T Loftsson, P Saokham, ARS Couto - International journal of pharmaceutics, 2019 - Elsevier
Cyclodextrins (CDs) are oligosaccharides that self-assemble in aqueous solutions to form
transient clusters, nanoparticles and small microparticles. The critical aggregation …

[HTML][HTML] Hypoxia-responsive lipid-poly-(hypoxic radiosensitized polyprodrug) nanoparticles for glioma chemo-and radiotherapy

L Hua, Z Wang, L Zhao, H Mao, G Wang, K Zhang… - Theranostics, 2018 - ncbi.nlm.nih.gov
Abstract Treatment of malignant glioma is a challenge facing cancer therapy. In addition to
surgery, and chemotherapy, radiotherapy (RT) is one of the most effective modalities of …

Building nanostructures with drugs

W Ma, AG Cheetham, H Cui - Nano today, 2016 - Elsevier
The convergence of nanoscience and drug delivery has prompted the formation of the field
of nanomedicine, one that exploits the novel physicochemical and biological properties of …

Comparing organic and metallo-organic hydrazone molecular cages as potential carriers for doxorubicin delivery

G Montà-González, D Bastante-Rodríguez… - Chemical …, 2024 - pubs.rsc.org
Molecular cages are three-dimensional supramolecular structures that completely wrap
guest molecules by encapsulation. We describe a rare comparative study between a metallo …

Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

H Ijäs, B Shen, A Heuer-Jungemann… - Nucleic acids …, 2021 - academic.oup.com
Doxorubicin (DOX) is a common drug in cancer chemotherapy, and its high DNA-binding
affinity can be harnessed in preparing DOX-loaded DNA nanostructures for targeted delivery …

Doxorubicin-loaded cell-derived nanovesicles: An alternative targeted approach for anti-tumor therapy

WJ Goh, CK Lee, S Zou, ECY Woon… - International journal …, 2017 - Taylor & Francis
Cell-derived nanovesicles (CDNs) are an emerging class of biological drug delivery systems
(DDS) that retain the characteristics of the cells they were derived from, without the need for …