Quantitative computed tomography is being increasingly used to quantify the features of
chronic obstructive pulmonary disease, specifically emphysema, air trapping, and airway …

Lung densitometry assesses with computed tomography (CT) the X-ray attenuation of the
pulmonary tissue which reflects both the degree of inflation and the structural lung …

Rationale: Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation,
leading to accelerated lung aging, apoptosis, and emphysema, as well as systemic …

Background Emphysema is a key contributor to airflow limitation in chronic obstructive
pulmonary disease (COPD) and can be quantified using CT scanning. We investigated the …

Background Multiple studies have identified COPD subtypes by using visual or quantitative
evaluation of CT images. However, there has been no systematic assessment of a combined …

Background CT is used to quantify abnormal changes in the lung parenchyma of smokers
that might overlap chronic obstructive pulmonary disease (COPD), but studies on the …

Rationale: Computed tomography (CT)-based lung density is used to quantitate the
percentage of emphysema-like lung (hereafter referred to as percent emphysema), but …

Smoking is the main risk factor for lung cancer (LC), which is the leading cause of cancer-
related death worldwide. Independent randomized controlled trials, governmental and inter …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

This study presents a fully automatic, data-driven approach for texture-based quantitative
analysis of chronic obstructive pulmonary disease (COPD) in pulmonary computed …