By linking the past with the future, our memories define our sense of identity. Because human memory engages the conscious realm, its examination has historically been …
Y Zhang, L Cao, V Varga, M Jing… - Proceedings of the …, 2021 - National Acad Sciences
Learning and memory are assumed to be supported by mechanisms that involve cholinergic transmission and hippocampal theta. Using G protein–coupled receptor-activation–based …
Working memory (WM) is the ability to remember and manipulate information for short time intervals. Recent studies have proposed that sustained firing encoding the contents of WM is …
The prefrontal cortex regulates the expression of fear based on previously learned information. Recently, this brain area has emerged as being crucial in the initial formation of …
ML Furey, WC Drevets, EM Hoffman, E Frankel… - JAMA …, 2013 - jamanetwork.com
Context The need for improved treatment options for patients with major depressive disorder (MDD) is critical. Faster-acting antidepressants and biomarkers that predict clinical response …
T Kamigaki - Neuroscience research, 2019 - Elsevier
The essential role of executive control is to select the most appropriate behavior among other candidates depending on the sensory information (exogenous information) and on the …
Cholinesterase inhibitors are frequently used to treat cognitive symptoms in Lewy body dementias (Parkinson's disease dementia and dementia with Lewy bodies). However, the …
R Liu, J Crawford, PM Callahan, AV Terry… - Current Biology, 2017 - cell.com
Acetylcholine in the neocortex is critical for executive function [1–3]. Degeneration of cholinergic neurons in aging and Alzheimer's dementia is commonly treated with …
RJ Jaffe, C Constantinidis - Comprehensive Physiology, 2021 - ncbi.nlm.nih.gov
Working memory is the ability to maintain and manipulate information in the conscious mind over a timescale of seconds. This ability is thought to be maintained through the persistent …