A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Concise review: mesenchymal stem cells: from roots to boost

A Andrzejewska, B Lukomska, M Janowski - Stem cells, 2019 - academic.oup.com
It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …

Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?

U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …

Key transcription factors in the differentiation of mesenchymal stem cells

SG Almalki, DK Agrawal - Differentiation, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells that represent a promising source for
regenerative medicine. MSCs are capable of osteogenic, chondrogenic, adipogenic and …

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

H Nagai, Y Okazaki, SH Chew… - Proceedings of the …, 2011 - National Acad Sciences
Multiwalled carbon nanotubes (MWCNTs) have the potential for widespread applications in
engineering and materials science. However, because of their needle-like shape and high …

Functional heterogeneity of mesenchymal stem cells: implications for cell therapy

DG Phinney - Journal of cellular biochemistry, 2012 - Wiley Online Library
The term mesenchymal stem cell (MSCs) was adopted in the 1990s to describe a population
of bone‐marrow‐derived cells that demonstrated the capacity for tri‐lineage differentiation at …

Adult mesenchymal stem cells and cell-based tissue engineering

RS Tuan, G Boland, R Tuli - Arthritis Res Ther, 2002 - Springer
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult
human tissues, including bone marrow stroma and a number of connective tissues, has …

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

I Gonzalez, R Munita, E Agirre, TA Dittmer… - Nature structural & …, 2015 - nature.com
Alternative pre-mRNA splicing is a highly cell type–specific process essential to generating
protein diversity. However, the mechanisms responsible for the establishment and …

In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment

KC Russell, DG Phinney, MR Lacey, BL Barrilleaux… - Stem …, 2010 - academic.oup.com
In regenerative medicine, bone marrow is a promising source of mesenchymal stem cells
(MSCs) for a broad range of cellular therapies. This research addresses a basic prerequisite …

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

P Scaffidi, T Misteli - Nature cell biology, 2008 - nature.com
The premature-ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by
constitutive production of progerin, a mutant form of the nuclear architectural protein lamin …