Virtual screening web servers: designing chemical probes and drug candidates in the cyberspace

N Singh, L Chaput, BO Villoutreix - Briefings in bioinformatics, 2021 - academic.oup.com
The interplay between life sciences and advancing technology drives a continuous cycle of
chemical data growth; these data are most often stored in open or partially open databases …

Recent advances in in silico target fishing

S Galati, M Di Stefano, E Martinelli, G Poli, T Tuccinardi - Molecules, 2021 - mdpi.com
In silico target fishing, whose aim is to identify possible protein targets for a query molecule,
is an emerging approach used in drug discovery due its wide variety of applications. This …

Pharmacokinetics and drug-likeness of antidiabetic flavonoids: Molecular docking and DFT study

M Bitew, T Desalegn, TB Demissie, A Belayneh… - Plos one, 2021 - journals.plos.org
Computer aided toxicity and pharmacokinetic prediction studies attracted the attention of
pharmaceutical industries as an alternative means to predict potential drug candidates. In …

[HTML][HTML] Ethnopharmacological, phytochemistry and other potential applications of Dodonaea genus: A comprehensive review

F Beshah, Y Hunde, M Getachew, RK Bachheti… - Current Research in …, 2020 - Elsevier
Dodonaea (family Sapindaceae)-a genus of flowering plant (above 70 species recorded)
and used for various activities. Dodonaea viscosa, D. angustifolia, D. spatulate, D. polyandra …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

Phytochemicals from Nigerian medicinal plants modulate therapeutically-relevant diabetes targets: insight from computational direction

F Olawale, K Olofinsan, O Iwaloye… - Advances in Traditional …, 2021 - Springer
Traditional medicines have played critical roles in the treatment of diabetes in Nigeria. Since
plants extracts contain many phytochemical compounds, it is quite challenging to …

Computational study of asian propolis compounds as potential anti-type 2 diabetes mellitus agents by using inverse virtual screening with the DIA-DB web server …

PH Syaifie, AH Harisna, MAF Nasution, AG Arda… - Molecules, 2022 - mdpi.com
Propolis contains a wide range of pharmacological activities because of their various
bioactive compounds. The beneficial effect of propolis is interesting for treating type-2 …

Treasuring the computational approach in medicinal plant research

H Singh, N Bharadvaja - Progress in Biophysics and Molecular Biology, 2021 - Elsevier
Medicinal plants serve as a valuable source of secondary metabolites since time
immemorial. Computational Research in 21st century is giving more attention to medicinal …

[HTML][HTML] UHPLC-QToF-MS characterization of bioactive metabolites from Quercus robur L. grown in South Africa for antioxidant and antidiabetic properties

JO Unuofin, SL Lebelo - Arabian Journal of Chemistry, 2021 - Elsevier
The leaves and stem bark extracts of Quercus robur L. grown in South Africa have been
investigated for their bioactive metabolites using UHPLC-QToF-MS. The UHPLC-QToF-MS …

The use of South African botanical species for the control of blood sugar

IE Cock, N Ndlovu, SF Van Vuuren - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Diabetes mellitus (DM) is one of the most prevalent
diseases globally and is of considerable concern to global health. Approximately 425 million …