Progressive multifocal leukoencephalopathy: current insights

M Kartau, JOT Sipilä, E Auvinen… - Degenerative …, 2019 - Taylor & Francis
Cases of PML should be evaluated according to predisposing factors, as these subgroups
differ by incidence rate, clinical course, and prognosis. The three most significant groups at …

Complexities of JC polyomavirus receptor-dependent and-independent mechanisms of infection

J Morris-Love, WJ Atwood - Viruses, 2022 - mdpi.com
JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent
infection in most of the adult population. Immune-competent patients are generally …

Low frequency of opportunistic infections in patients receiving vedolizumab in clinical trials and post-marketing setting

SC Ng, IN Hilmi, A Blake, F Bhayat… - Inflammatory Bowel …, 2018 - academic.oup.com
Background Vedolizumab (ENTYVIO) is a humanized α4β7 integrin antagonist approved for
the treatment of inflammatory bowel disease, which selectively blocks gut-specific …

Progressive multifocal leukoencephalopathy and hematologic malignancies: a single cancer center retrospective review

EC Neil, LM DeAngelis - Blood Advances, 2017 - ashpublications.org
Progressive multifocal leukoencephalopathy (PML) is an uncommon opportunistic infection
with high morbidity and mortality. This is an institutional review board–approved …

A human-derived 3D brain organoid model to study JC virus infection

P Barreras, D Pamies, MC Monaco, LS Muñoz… - Journal of …, 2022 - Springer
Progressive multifocal leukoencephalopathy (PML) is a frequent neurological complication
in immunosuppressed patients. PML is caused by the JC virus (JCV), a neurotropic DNA …

Approach to an intracranial mass in patients with HIV

I Elicer - Current Neurology and Neuroscience Reports, 2020 - Springer
Abstract Purpose of Review Space-occupying lesions represent a diagnostic challenge
among people with the human immunodeficiency virus, acquired immunodeficiency …

Osteoclast ultrastructure in Paget's disease

A Rebel, K Malkani, M Basle, CH Bregeon - Calcified tissue research, 1976 - Springer
The ultrastructural study of osteoclasts in biopsies from 12 patients with Paget's disease
reveals several cytological anomalies. In particular, nuclear inclusions, consisting …

Identification of microbes using single-layer graphene-based nano biosensors

M Makwana, AM Patel - Journal of Molecular Modeling, 2023 - Springer
Context Graphene based nano sensors have huge potential in an era of sensor technology.
The objective of this study is to create a sensor by investigating the vibration responses of …

What is the risk of progressive multifocal leukoencephalopathy in patients with ulcerative colitis or Crohn's disease treated with vedolizumab?

T Card, J Xu, H Liang, F Bhayat - Inflammatory Bowel Diseases, 2018 - academic.oup.com
Background Progressive multifocal leukoencephalopathy is a serious condition linked to
certain diseases and immunosuppressant therapies, including the α4 integrin antagonist …

Biogenesis of JC polyomavirus associated extracellular vesicles

J Morris‐Love, BA O'Hara, GV Gee… - Journal of …, 2022 - Wiley Online Library
JC polyomavirus (JCPyV) is a small, non‐enveloped virus that persists in the kidney in about
half the adult population. In severely immune‐compromised individuals JCPyV causes the …