Chronic or intermittent hyperglycemia is associated with the development of diabetic
complications. Several signaling pathways can be altered by having hyperglycemia in …

Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Oxidative stress is mainly caused by intracellular reactive oxygen species (ROS) production,
which is highly associated with normal physiological homeostasis and the pathogenesis of …

Various studies, especially in recent years, have shown that quercetin has beneficial
therapeutic effects in various human diseases, including diabetes. Quercetin has significant …

The incidence of diabetes has been increasing in recent decades which is affecting the
population of both, developed and developing countries. Diabetes is associated with micro …

Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus
(DM) causing vision impairment even at young ages. There are numerous mechanisms …

Diabetes mellitus (DM) is a major endocrine metabolic disease and is marked by a lack of
insulin. The complication of DM is one of the most difficult problems in medicine. The initial …

Background: The mammalian circadian clock and its associated clock genes are
increasingly been recognized as critical components for a number of physiological and …

Diabetic retinopathy (DR) seriously endangers human beings' health, uncovering the
underlying mechanism might help to cure DR. In this study, we found that the effects of …

Diabetic retinopathy (DR) is a serious blinding complication of diabetes. At present, the
therapeutic intervention effect is limited. We aimed to investigate the circRNA expression …