[HTML][HTML] Surgical considerations for older adults with cancer: a multidimensional, multiphase pathway to improve care

I Montroni, NM Saur, A Shahrokni… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
By 2040, the incidence of solid cancers among patients older than 70 years will increase
from 1.2 million to 2.2 million in North America alone. 1 Older adults with cancer are at …

[HTML][HTML] Challenges in geriatric oncology—a surgeon's perspective

R Parks, KL Cheung - Current Oncology, 2022 - mdpi.com
As our global population ages, we will see more cancer diagnoses in older adults. Surgery
is an important treatment modality for solid tumours, forming the majority of all cancers …

GOSAFE-Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery: early analysis on 977 patients

I Montroni, S Rostoft, A Spinelli… - Journal of Geriatric …, 2020 - Elsevier
Objective Older patients with cancer value functional outcomes as much as survival, but
surgical studies lack functional recovery (FR) data. The value of a standardized frailty …

m6A RNA methylation regulators contribute to malignant progression in rectal cancer

J Zhuang, C Lin, J Ye - Journal of Cellular Physiology, 2020 - Wiley Online Library
Abstract N6, 2′‐O‐dimethyladenosine (m6A) RNA methylation, which is correlated with
cancer initiation and progression, is dynamically regulated by m6A RNA methylation …

Association of age with outcomes in locally advanced rectal cancer treated with neoadjuvant therapy followed by surgery

S Sonal, YZ Qwaider, C Boudreau, H Kunitake… - The American Journal of …, 2023 - Elsevier
Introduction We aimed to assess the association of age with outcomes in patients with
Locally Advanced Rectal Cancer (LARC) who received neoadjuvant therapy followed by …

Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England

JC Taylor, LH Iversen, D Burke, PJ Finan… - Colorectal …, 2021 - Wiley Online Library
Abstract Aim Denmark and Yorkshire are demographically similar and both have undergone
changes in their management of colorectal cancer to improve outcomes. The differential …

A comparison of frailty measures in population-based data for patients with colorectal cancer

R Birch, J Taylor, T Rahman, R Audisio… - Age and …, 2024 - academic.oup.com
Background Numerous studies have revealed age-related inequalities in colorectal cancer
care. Increasing levels of frailty in an ageing population may be contributing to this, but …

[HTML][HTML] Exploring determinants of interdisciplinary collaboration within a geriatric oncology setting: a mixed-method study

M Barrault-Couchouron, N Micheli, P Soubeyran - Cancers, 2022 - mdpi.com
Simple Summary Collaboration between oncologists and geriatricians has been shown to
improve the quality of elderly cancer patient care. However, previous research has revealed …

[HTML][HTML] Surgery for rectal cancer: Differences in resection rates among hospitals in the Netherlands

LJX Giesen, PB Olthof, MAG Elferink, C Verhoef… - European Journal of …, 2021 - Elsevier
Aim Numerous quality improvement initiatives for rectal cancer surgery have focused on
textbook outcome parameters. In these studies, resection rate and patients who did not …

[HTML][HTML] Changes in rectal cancer treatment after the introduction of a national screening program; Increasing use of less invasive strategies within a national cohort

LJX Giesen, PB Olthof, MAG Elferink… - European Journal of …, 2022 - Elsevier
Aim Organ preserving treatment strategies and the introduction of a colorectal cancer-
screening program have likely influenced the resection rates of rectal cancer. The aim of this …