Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Transition metal complexes as photosensitisers in one-and two-photon photodynamic therapy

LK McKenzie, HE Bryant, JA Weinstein - Coordination Chemistry Reviews, 2019 - Elsevier
Photodynamic therapy (PDT) exploits light-activated compounds for therapeutic use. It relies
on a photosensitiser (PS) that is inactive in the absence of light. When irradiated, the PS …

Structurally simple osmium (II) polypyridyl complexes as photosensitizers for photodynamic therapy in the near infrared

A Mani, T Feng, A Gandioso, R Vinck… - Angewandte …, 2023 - Wiley Online Library
Five osmium (II) polypyridyl complexes of the general formula [Os (4, 7‐diphenyl‐1, 10‐
phenanthroline) 2L] 2+ were synthesized as photosensitizers for photodynamic therapy by …

Photodynamic Therapy of Inorganic Complexes for the Treatment of Cancer

CB Smith, LC Days, DR Alajroush… - Photochemistry and …, 2022 - Wiley Online Library
Photodynamic therapy (PDT) is a medicinal tool that uses a photosensitizer and a light
source to treat several conditions, including cancer. PDT uses reactive oxygen species such …

Perspectives of molecular and nanostructured systems with d-and f-block metals in photogeneration of reactive oxygen species for medical strategies

J Kuncewicz, JM Dąbrowski, A Kyzioł, M Brindell… - Coordination Chemistry …, 2019 - Elsevier
The photogeneration of reactive oxygen species (ROS) by molecular and nanostructured
systems with d-and f-metal compounds is discussed with the emphasis on the mechanisms …

A multiscale free energy method reveals an unprecedented photoactivation of a bimetallic Os (II)–Pt (II) dual anticancer agent

ME Alberto, A Francés-Monerris - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
The photoreactivity of relatively large transition metal complexes is often limited to the
description of the static potential energy surfaces of the involved electronic states. While …

Exploring the activity of a polyazine bridged Ru (II)–Pt (II) supramolecule in F98 rat malignant glioma cells

J Zhu, JA Rodriguez-Corrales, R Prussin… - Chemical …, 2017 - pubs.rsc.org
The mixed-metal supramolecular complex,[(Ph2phen) 2Ru (dpp) PtCl2] 2+, displays
significant DNA modification, cell growth inhibition, and toxicity towards F98 malignant …

Ru (II) Oxygen Sensors for Co (III) Complexes and Amphotericin B Antifungal Activity Detection by Phosphorescence Optical Respirometry

K Turecka, A Chylewska, AM Dąbrowska… - International Journal of …, 2023 - mdpi.com
The measurement of oxygen consumption is an important element in the understanding of
an organism's metabolic state. Oxygen is also a phosphorescence quencher, which allows …

Panchromatic osmium complexes for photodynamic therapy: solutions to existing problems and new questions

EC Glazer - Photochemistry and photobiology, 2017 - Wiley Online Library
This article is a highlight of the paper by Lazic et al. in this issue of Photochemistry and
Photobiology, https://doi. org/10.1111/php. 12767. It describes the validation of osmium …

Pushing the limits of structurally-diverse light-harvesting Ru (II) metal-organic chromophores for photodynamic therapy

R Padilla, WA Maza, AJ Dominijanni… - … of Photochemistry and …, 2016 - Elsevier
The synthesis of Ru (II) derivatives [(AnthbpyMe)(bpy) Ru (dpp)] 2+(2) and [(AnthbpyMe) 2
Ru (dpp)] 2+(3), and the analysis of their excited state properties as well as their …