HIV-1 infection requires nuclear entry of the viral genome. Previous evidence suggests that
this entry proceeds through nuclear pore complexes (NPCs), with the 120× 60 nm capsid …

HIV can infect non-dividing cells because the viral capsid can overcome the selective barrier
of the nuclear pore complex and deliver the genome directly into the nucleus,. Remarkably …

The human immunodeficiency virus type 1 (HIV-1) capsid is a protein core formed by
multiple copies of the viral capsid (CA) protein. Inside the capsid, HIV-1 harbours all the viral …

The recent revolution in imaging techniques and results from RNA footprinting in situ reveal
how the bacteriophage MS2 genome regulates both particle assembly and genome release …

Summary Human myxovirus resistance 2 (MX2) can restrict HIV-1 and herpesviruses at a
post-entry step through a process requiring an interaction between MX2 and the viral …

The widespread application of genome editing to treat and cure disease requires the
delivery of genome editors into the nucleus of target cells. Enveloped delivery vehicles …

The HIV-1 capsid is composed of capsid (CA) protein hexamers and pentamers (capsomers)
that contain a central pore hypothesised to regulate capsid assembly and facilitate …

HIV-1 infection requires passage of the viral core through the nuclear pore of the cell, a
process that depends on functions of the viral capsid. Recent studies have shown that HIV-1 …

Structured illumination microscopy (SIM) has emerged as a promising super-resolution
fluorescence imaging technique, offering diverse configurations and computational …

Recent findings suggest that HIV-1 capsids mimic nuclear transport receptors to engage FG-
nucleoporins for entry into host nuclei. In this issue of Cell Host & Microbe, Moschonas et al …