Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis

J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang… - Cell research, 2020 - nature.com
Lung injury and fibrosis represent the most significant outcomes of severe and acute lung
disorders, including COVID-19. However, there are still no effective drugs to treat lung injury …

Recent methodology advances in fluorescence molecular tomography

Y An, K Wang, J Tian - Visual Computing for Industry, Biomedicine, and Art, 2018 - Springer
Molecular imaging (MI) is a novel imaging discipline that has been continuously developed
in recent years. It combines biochemistry, multimodal imaging, biomathematics …

Targeted migration of bone marrow mesenchymal stem cells inhibits silica-induced pulmonary fibrosis in rats

X Li, G An, Y Wang, D Liang, Z Zhu, L Tian - Stem Cell Research & …, 2018 - Springer
Background Silicosis is a common occupational disease, characterized by silicotic nodules
and diffuse pulmonary fibrosis. We demonstrated an anti-fibrotic effect of bone marrow …

Enhanced tumor accumulation and therapeutic efficacy of liposomal drugs through over-threshold dosing

H Ao, Z Wang, L Lu, H Ma, H Li, J Fu, M Li… - Journal of …, 2022 - Springer
Background Most intravenously administered drug-loaded nanoparticles are taken up by
liver Kupffer cells, and only a small portion can accumulate at the tumor, resulting in an …

Robust reconstruction of fluorescence molecular tomography based on sparsity adaptive correntropy matching pursuit method for stem cell distribution

S Zhang, X Ma, Y Wang, M Wu, H Meng… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Fluorescence molecular tomography (FMT), as a promising imaging modality in preclinical
research, can obtain the three-dimensional (3-D) position information of the stem cell in …

In vivo three-dimensional evaluation of tumour hypoxia in nasopharyngeal carcinomas using FMT-CT and MSOT

W Huang, K Wang, Y An, H Meng, Y Gao… - European journal of …, 2020 - Springer
Purpose Accurate evaluation of hypoxia is particularly important in patients with
nasopharyngeal carcinoma (NPC) undergoing radiotherapy. The aim of this study was to …

A fast and automated FMT/XCT reconstruction strategy based on standardized imaging space

Y An, C Bian, D Yan, H Wang, Y Wang… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
The traditional finite element method-based fluorescence molecular tomography (FMT)/X-
ray computed tomography (XCT) imaging reconstruction suffers from complicated mesh …

High-resolution reconstruction of FMT based on elastic net optimized by relaxed ADMM

D Yan, Y An, G Li, J Li, Y Du… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Fluorescence Molecular Tomography (FMT), providing thethree-dimensional fluorescent
distribution information of specific molecular probes in tumors, is widely applied to detect in …

Design and validation of a simple device for insufflation of dry powders in a mice model

B Chaurasiya, M Zhou, J Tu, C Sun - European Journal of Pharmaceutical …, 2018 - Elsevier
Delivery of inhalational dry powders (DPs) to the lung of mice is pivotal for pre-clinical
pharmacokinetic and pharmacodynamic investigations. Although several devices have been …

Reconstruction based on adaptive group least angle regression for fluorescence molecular tomography

Y An, H Wang, J Li, G Li, X Ma, Y Du… - Biomedical Optics …, 2023 - opg.optica.org
Fluorescence molecular tomography can combine two-dimensional fluorescence imaging
with anatomical information to reconstruct three-dimensional images of tumors …