Taxonomic and functional changes to the composition of the gut microbiome have been
implicated in multiple human diseases. Recent microbiome genome-wide association …

The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

Background Obesity is the cause of cardiovascular diseases and other diseases, leading to
increased medical costs, and causing a great burden to individuals, families and society …

Intestinal microbiota changes are associated with the development of obesity. However,
studies in humans have generated conflicting results due to high inter-individual …

Aging-associated alterations in composition, diversity and functional features of intestinal
microbiota are well-described in the modern literature. They are suggested to be caused by …

Humans consider themselves discrete autonomous organisms, but recent research is
rapidly strengthening the appreciation that associated microorganisms make essential …

Scope Age‐related degeneration is associated with imbalances of gut microbiota and its
related immune system, thus gut microbiota dysbiosis is considered to be a key target to …

Gut microbiota can influence the aging process and may modulate aging‐related changes in
cognitive function. Trimethylamine‐N‐oxide (TMAO), a metabolite of intestinal flora, has …

The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which
contributes to a variety of physiological functions. The GM is highly dynamic, being sensitive …

Current understanding on the mechanisms of brain injury and neurodegeneration highlights
an appreciation of multicellular interactions within the neurovascular unit (NVU), which …