The relationship between dietary fat and glucose metabolism has been recognized for at
least 60 years. In experimental animals, high fat diets result in impaired glucose tolerance …

For many years, there was little interest in the biochemistry or physiology of adipose tissue. It
is now well recognized that adipocytes play an important dynamic role in metabolic …

Based on our previous finding that desensitization of the insulin-responsive glucose
transport system (GTS) requires three components, glucose, insulin, and glutamine, we …

Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …

We have examined the onset and duration of the inhibitory effect of an intravenous infusion
of lipid/heparin on total body carbohydrate and fat oxidation (by indirect calorimetry) and on …

Fully differentiated 3T3-L1 adipocytes were chronically exposed to 5 nM tumor necrosis
factor-alpha (TNF). This resulted in the development of an insulin resistance based on the …

High-fat feeding induces insulin resistance and increases the risk for the development of
diabetes and coronary artery disease. Glucocorticoids exacerbate this hyperinsulinemic …

We have developed an in vitro muscle preparation suitable for metabolic studies with human
muscle tissue and have investigated the effects of obesity and non-insulin-dependent …

Insulin stimulates glucose transport in rat adipose cells through the translocation of glucose
transporters from an intracellular pool to the plasma membrane. A detailed characterization …

We have examined peripheral insulin action in conscious rats chronically fed high fat (60%
calories as fat) or high carbohydrate (lab chow) diets using the euglycaemic clamp plus 3 H …