Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs. Recent technological advances have in part overcome problems with their circular …
LS Kristensen, T Jakobsen, H Hager… - Nature reviews Clinical …, 2022 - nature.com
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily non-coding RNA molecules, many of which have key roles in cancer development and …
The removal of introns from mRNA precursors and its regulation by alternative splicing are key for eukaryotic gene expression and cellular function, as evidenced by the numerous …
S Misir, N Wu, BB Yang - Cell Death & Differentiation, 2022 - nature.com
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by their covalently closed circular structure, have become a new research paradigm in RNA …
Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes as well as from the processing of cellular housekeeping noncoding RNAs and precursor …
Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across species ranging from viruses to mammals. Important advances …
AT He, J Liu, F Li, BB Yang - Signal transduction and targeted therapy, 2021 - nature.com
Significant progress has been made in circular RNA (circRNA) research in recent years. Increasing evidence suggests that circRNAs play important roles in many cellular processes …
B Li, L Zhu, C Lu, C Wang, H Wang, H Jin, X Ma… - Nature …, 2021 - nature.com
Circular RNAs (circRNA) are a class of covalently closed single-stranded RNAs that have been implicated in cancer progression. Here we identify circNDUFB2 to be downregulated …
X Liu, Y Zhang, S Zhou, L Dain, L Mei, G Zhu - Journal of Controlled …, 2022 - Elsevier
Circular RNAs (circRNA) is a class of natural (biogenic) or synthetic closed RNA without 5′ or 3′ ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA …