MetDecode: methylation-based deconvolution of cell-free DNA for noninvasive multi-cancer typing
A Passemiers, S Tuveri, D Sudhakaran… - …, 2024 - academic.oup.com
Motivation Circulating-cell free DNA (cfDNA) is widely explored as a noninvasive biomarker
for cancer screening and diagnosis. The ability to decode the cells of origin in cfDNA would …
for cancer screening and diagnosis. The ability to decode the cells of origin in cfDNA would …
Cancer neuroscience and glioma: clinical implications
In recent years, it has been increasingly recognized that tumor growth relies not only on
support from the surrounding microenvironment but also on the tumors capacity to adapt to …
support from the surrounding microenvironment but also on the tumors capacity to adapt to …
A novel method for cell deconvolution using DNA methylation in PCA space
H Xu, G Zhang, J Chen - BMC genomics, 2024 - Springer
Background In this study, we present a novel method for reference-based cell deconvolution
using data from DNA methylation arrays. Different from existing methods like IDOL-Ext …
using data from DNA methylation arrays. Different from existing methods like IDOL-Ext …