The majority of human mRNAs generate alternative 3′ untranslated regions (UTRs)
through various processes, including RNA modifications such as RNA editing, m 6 A …

Background Alternative splicing (AS), a posttranscriptional process, contributes to the
complexity of transcripts from a limited number of genes in a genome, and AS is considered …

Cleavage and polyadenylation of pre-mRNAs is a necessary step for gene expression and
function. Majority of human genes exhibit multiple polyadenylation sites, which can be …

Alternative pre-mRNA splicing is a critical mechanism that generates multiple mRNA from a
single gene, thereby increasing the diversity of the proteome. Recent research has …

Background Human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with
relevance in several cancers. The aim of this study was to evaluate the potential role of …

O-GlcNAcylation, a recently discovered post-translational modification of proteins, plays a
crucial role in regulating protein structure and function, and is closely associated with …

Antigen-specific antibodies are generated by antibody-secreting cells (ASCs). How RNA
post-transcriptional modification affects antibody homeostasis remains unclear. Here, we …

The cancer-associated alternative splicing (AS) events generate cancer-related transcripts
which are involved in uncontrolled cell proliferation and drug resistance. However, the key …

Alternative pre-mRNA splicing (AS) is a biological process that results in proteomic diversity.
However, implications of AS alterations in cancer remain poorly understood. Herein, we …

Background The identification of cancer driver genes from sequencing data has been crucial
in deepening our understanding of tumor biology and expanding targeted therapy options …