Nanoparticle-based materials in anticancer drug delivery: Current and future prospects

S Ajith, F Almomani, A Elhissi, GA Husseini - Heliyon, 2023 - cell.com
The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of
the most common cancer treatment modalities is chemotherapy which involves …

Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling

F Moradi Kashkooli, TK Hornsby… - Wiley …, 2024 - Wiley Online Library
Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …

A spatiotemporal computational model of focused ultrasound heat-induced nano-sized drug delivery system in solid tumors

F Moradi Kashkooli, M Souri, J Tavakkoli… - Drug Delivery, 2023 - Taylor & Francis
Focused Ultrasound (FUS)-triggered nano-sized drug delivery, as a smart stimuli-responsive
system for treating solid tumors, is computationally investigated to enhance localized …

A 3D numerical model of controlled drug delivery to solid tumor by means of mild microwave hyperthermia-activated thermo-sensitive liposomes

G Adabbo, A Andreozzi, M Iasiello, PA Netti… - International Journal of …, 2023 - Elsevier
A computational 3D analysis of liposomal drug delivery to investigate the effectiveness of
this innovative therapy as an alternative to conventional chemotherapy is shown in this …

Stimuli-sensitive nano-drug delivery with programmable size changes to enhance accumulation of therapeutic agents in tumors

M Souri, M Kiani Shahvandi, M Chiani… - Drug Delivery, 2023 - Taylor & Francis
Nano-based drug delivery systems hold significant promise for cancer therapies. Presently,
the poor accumulation of drug-carrying nanoparticles in tumors has limited their success. In …

A comparative study between conventional chemotherapy and photothermal activated nano-sized targeted drug delivery to solid tumor

MK Shahvandi, M Souri, S Tavasoli… - Computers in Biology …, 2023 - Elsevier
Delivery of chemotherapeutic medicines to solid tumors is critical for optimal therapeutic
success and minimal adverse effects. We mathematically developed a delivery method …

Optimization of laser dosimetry based on patient-specific anatomical models for the ablation of pancreatic ductal adenocarcinoma tumor

P Namakshenas, FM Di Matteo, L Bianchi, E Faiella… - Scientific Reports, 2023 - nature.com
Laser-induced thermotherapy has shown promising potential for the treatment of
unresectable primary pancreatic ductal adenocarcinoma tumors. Nevertheless …

Fiber Bragg grating sensors-based assessment of laser ablation on pancreas at 808 and 1064 nm using a diffusing applicator: experimental and numerical study

P Namakshenas, L Bianchi… - IEEE Sensors …, 2023 - ieeexplore.ieee.org
Laser ablation (LA) holds great promise for the localized treatment of pancreatic tumors.
However, there are still many technical aspects that require improvements before largely …

[HTML][HTML] Numerical evaluation of heat-triggered drug release via thermo-sensitive liposomes: A comparison between image-based vascularized tumor and volume …

G Adabbo, A Andreozzi, M Iasiello, GP Vanoli - International Journal of Heat …, 2024 - Elsevier
In this study, two numerical models for controlled drug delivery through thermo-sensitive
liposomes under mild microwave hyperthermia are compared. The first model simulates …

Surface modification of graphene oxide by functionalized dendritic polyesters based on phthalic acid and pentaerythritol as a novel nanoplatform for sustained drug …

NT Fard, HA Panahi, MD Banadaki, E Moniri… - Materials Today …, 2023 - Elsevier
In this work, the third generation of polyester dendrimers was synthesized by conjugating
phthalic acid and pentaerythritol on the graphene oxide surface. After the esterification …