[HTML][HTML] Sirtuins at the service of healthy longevity
M Watroba, D Szukiewicz - Frontiers in Physiology, 2021 - frontiersin.org
Sirtuins may counteract at least six hallmarks of organismal aging: neurodegeneration,
chronic but ineffective inflammatory response, metabolic syndrome, DNA damage, genome …
chronic but ineffective inflammatory response, metabolic syndrome, DNA damage, genome …
SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
SLC25A51 selectively imports oxidized NAD+ into the mitochondrial matrix and is required
for sustaining cell respiration. We observed elevated expression of SLC25A51 that …
for sustaining cell respiration. We observed elevated expression of SLC25A51 that …
[HTML][HTML] Reduced SIRT1 and SIRT3 and lower antioxidant capacity of seminal plasma is associated with shorter sperm telomere length in oligospermic men
Infertility affects millions of couples worldwide and has a profound impact not only on their
families, but also on communities. Telomere attrition has been associated with infertility …
families, but also on communities. Telomere attrition has been associated with infertility …
SLC25A51 impacts drug sensitivity in AML cells by sustaining mitochondrial oxidative flux
Abstract SLC25A51 imports oxidized NAD+ into the mitochondrial matrix and is required for
sustaining oxidative metabolism in human mitochondria. We observed that higher …
sustaining oxidative metabolism in human mitochondria. We observed that higher …