Through the layers: how macrophages drive atherosclerosis across the vessel wall

LI Susser, KJ Rayner - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …

Netrin-1: An emerging player in inflammatory diseases

X Xia, Z Hu, S Wang, K Yin - Cytokine & Growth Factor Reviews, 2022 - Elsevier
Netrin-1 is a member of the laminin-like protein family and was initially identified as a potent
chemotactic molecule involved in axonal guidance and cell migration during embryonic …

Silencing myeloid netrin-1 induces inflammation resolution and plaque regression

M Schlegel, M Sharma, EJ Brown… - Circulation …, 2021 - Am Heart Assoc
Rationale: Therapeutic efforts to decrease atherosclerotic cardiovascular disease risk have
focused largely on reducing atherogenic lipoproteins, yet lipid-lowering therapies alone are …

GCN-GENE: a novel method for prediction of coronary heart disease-related genes

T Zhang, Y Lin, W He, FX Yuan, Y Zeng… - Computers in Biology and …, 2022 - Elsevier
Coronary heart disease is the most common heart disease, it can induce myocardial
infarction, and the cause of the disease has a lot to do with life and eating habits. The results …

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

M Cai, Q Zheng, Y Chen, S Liu, H Zhu… - Frontiers in Molecular …, 2024 - frontiersin.org
Netrin-1 was initially discovered as a neuronal growth cue for axonal guidance, and its
functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and …

Common Polymorphisms in the RGMa Promoter Are Associated With Cerebrovascular Atherosclerosis Burden in Chinese Han Patients With Acute Ischemic …

Q Hu, Z Chen, X Yuan, S Li, R Zhang… - Frontiers in …, 2021 - frontiersin.org
Repulsive guidance molecule a (RGMa) plays a vital role in the progression of numerous
inflammatory diseases. However, whether it participates in atherosclerosis development is …

[HTML][HTML] Association between serum netrin-1, netrin-4 and risk of the acute coronary syndrome in patients with type 2 diabetes mellitus-A pilot study

K Inderjeet, PS Adole, KV Vinod, AA Pillai - Indian Heart Journal, 2022 - Elsevier
The present study was done to assess the diagnostic utility of serum netrin-1 and netrin-4 for
recognising the acute coronary syndrome (ACS) in type 2 diabetes mellitus (T2DM) patients …

Macrophages in health and non-infectious disease

EE Bezsonov, A Gratchev, AN Orekhov - Biomedicines, 2021 - mdpi.com
In this Special Issue of Biomedicines, we have many insightful reviews and research papers
on the subject “Macrophages in Health and Non-infectious Disease”, but first; we should …

[PDF][PDF] Netrin-1 isoforms and macrophage phenotype: role in the pathophysiology of atherosclerosis

VAM Claro - kclpure.kcl.ac.uk
Atherosclerosis is a chronic inflammatory disease and is the main cause of ischaemic heart
disease, stroke, and other cardiovascular diseases. The development of atherosclerotic …

[PDF][PDF] Neuroimmune guidance cues in ascular (patho) ph siolog

D Vreeken - scholarlypublications …
Eph receptors and their ephrin ligands are important guidance molecules during
neurological and vascular development. In recent years it has become clear that the Eph …