Abstract Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein
belonging to the fibrinogen-related domain family. It has been localized to elastic fiber-rich …

Rationale: Atherosclerotic lesions are known for their cellular heterogeneity, yet the
molecular complexity within the cells of human plaques has not been fully assessed …

Endoplasmic reticulum is a principal organelle responsible for folding, post-translational
modifications and transport of secretory, luminal and membrane proteins, thus palys an …

Objective—Vascular adventitia encompasses progenitors and is getting recognized as the
major site of inflammation in early stage of atherosclerosis. However, the cellular atlas of the …

Endometrial cancer (EC) is a highly heterogeneous malignancy characterized by varied
pathology and prognoses, and the heterogeneity of its cancer cells and the tumor …

Background While single‐omics analyses on human atherosclerotic plaque have been very
useful to map stage‐or disease‐related differences in expression, they only partly capture …

Aims: Media-to-intima migration of vascular smooth muscle cells (VSMCs) is critical to
intimal thickening in atherosclerosis and restenosis after coronary angioplasty. The aim of …

Objective: Phenotypic switching of vascular smooth muscle cells (VSMCs) plays a critical
role in atherosclerosis, vascular restenosis, and hypertension. Choline exerts …

Renal fibrosis, which is characterized by excessive extracellular matrix (ECM) accumulation
in the renal tubulointerstitium, can lead to chronic kidney disease (CKD). The role of …

Ethnopharmacological relevance Aloe vera (L.) Burm. f.(Liliaceae family) is a well-known
traditional medicinal plant, that has been used to treat a variety of illnesses, for decades …