Clinical course and management of COVID-19 in the era of widespread population immunity

EA Meyerowitz, J Scott, A Richterman, V Male… - Nature Reviews …, 2024 - nature.com
The clinical implications of COVID-19 have changed since SARS-CoV-2 first emerged in
humans. The current high levels of population immunity, due to prior infection and/or …

COVID-19 annual update: a narrative review

M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Remdesivir: a review in COVID-19

HA Blair - Drugs, 2023 - Springer
Remdesivir (Veklury®), a nucleotide analogue prodrug with broad-spectrum antiviral activity,
is approved for the treatment of coronavirus disease 2019 (COVID-19), the illness caused by …

Is antiviral treatment at the acute phase of COVID-19 effective for decreasing the risk of long-COVID? A systematic review

C Fernández-de-Las-Peñas, J Torres-Macho… - Infection, 2024 - Springer
Purpose Preliminary evidence suggests a potential effect of antiviral medication used during
the acute COVID-19 phase for preventing long-COVID. This review investigates if having …

Expert consensus: main risk factors for poor prognosis in COVID-19 and the implications for targeted measures against SARS-CoV-2

FJ Candel, P Barreiro, M Salavert, A Cabello… - Viruses, 2023 - mdpi.com
The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus
type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …

Global landscape of COVID-19 research: a visualization analysis of randomized clinical trials

SH Zyoud - Clinical and Experimental Medicine, 2024 - Springer
The emergence of COVID-19 in 2019 has resulted in a significant global health crisis.
Consequently, extensive research was published to understand and mitigate the disease. In …

Impact of some antiviral drugs on health care utilization for patients with COVID-19: a systematic review and meta-analysis

B Wei, R Zhang, H Zeng, L Wu, R He… - Expert Review of Anti …, 2023 - Taylor & Francis
Background We aimed to assess the impact of antiviral drugs (fluvoxamine, remdesivir,
lopinavir/ritonavir (LPV/r), molnupiravir, andnirmatrelvir/ritonavir (NRV/r)) on health care …

A Comparative Analysis of COVID-19 Response Measures and Their Impact on Mortality Rate

T Konishi - COVID, 2024 - mdpi.com
(1) Background: The coronavirus disease 2019 (COVID-19) pandemic significantly affected
the population worldwide, with varying responses implemented to control its spread. This …

Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial

S Chevret, L Bouadma, C Dupuis, C Burdet… - Annals of Intensive …, 2023 - Springer
Background The respective benefits of high and low doses of dexamethasone (DXM) in
patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) and acute …

Recent advances in antivirals for Japanese encephalitis virus

Y Zhu, S Chen, Q Lurong, Z Qi - Viruses, 2023 - mdpi.com
Culex mosquitoes are the primary vectors of the Japanese encephalitis virus (JEV). Since its
discovery in 1935, Japanese encephalitis (JE), caused by JEV, has posed a significant …