[HTML][HTML] Phytochemicals in drug discovery—A confluence of tradition and innovation
Phytochemicals have a long and successful history in drug discovery. With recent
advancements in analytical techniques and methodologies, discovering bioactive leads from …
advancements in analytical techniques and methodologies, discovering bioactive leads from …
Camptothecin and its derivatives: Advancements, mechanisms and clinical potential in cancer therapy
Camptothecin (CPT), an alkaloid isolated from the Camptotheca tree, has demonstrated
significant anticancer properties in a range of malignancies. However, its therapeutic …
significant anticancer properties in a range of malignancies. However, its therapeutic …
[HTML][HTML] Green Extraction of Plant Materials Using Supercritical CO2: Insights into Methods, Analysis, and Bioactivity
In recent years, the supercritical CO2 extraction method has gained attention due to its use
of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that …
of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that …
[HTML][HTML] Phytochemical-mediated modulation of signaling pathways: A promising avenue for drug discovery
JK Paul, M Azmal, ANMSNB Haque… - Advances in Redox …, 2024 - Elsevier
Phytochemicals are bioactive compounds derived from plants, renowned for their
therapeutic potential. This study explores their pivotal roles in therapy and drug …
therapeutic potential. This study explores their pivotal roles in therapy and drug …
Unraveling the mechanism of carbonic anhydrase IX inhibition by alkaloids from Ruta chalepensis: A synergistic analysis of in vitro and in silico data
Due to the pivotal role of carbonic anhydrase IX (CA IX) in pathological conditions, there's a
pressing need for novel inhibitors to improve patient outcomes and clinical management …
pressing need for novel inhibitors to improve patient outcomes and clinical management …
[HTML][HTML] Hydrogels with Essential Oils: Recent Advances in Designs and Applications
M Chelu - Gels, 2024 - pmc.ncbi.nlm.nih.gov
The innovative fusion of essential oils with hydrogel engineering offers an optimistic
perspective for the design and development of next-generation materials incorporating …
perspective for the design and development of next-generation materials incorporating …
Genetic-bioengineering of nanotechnology in cell-specific pharmaceutical targeting: Biological, pharmacological, and biochemical impact of nanomaterials-based …
Addressing breast cancer is an ongoing global health concern, demanding constant
progress in treatment approaches due to its high incidence and mortality rates. In recent …
progress in treatment approaches due to its high incidence and mortality rates. In recent …
[HTML][HTML] Unveiling the Anticancer Potential: Computational Exploration of Nitrogenated Derivatives of (+)-Pancratistatin as Topoisomerase I Inhibitors
Cancer poses a substantial global health challenge, driving the need for innovative
therapeutic solutions that offer improved effectiveness and fewer side effects …
therapeutic solutions that offer improved effectiveness and fewer side effects …
Network pharmacology and molecular docking insights into Sirtuin-2 inhibitors (AK-7 and AGK-2): A synergistic strategy for COPD treatment
V Yadav, V Pandey, P Gaglani, A Srivastava - Human Gene, 2025 - Elsevier
Objective In the present study network pharmacology analysis of AGK-2 and AK-7 (SIRT-2
inhibitors) were performed to elucidate their mechanism in regulating COPD pathogenesis …
inhibitors) were performed to elucidate their mechanism in regulating COPD pathogenesis …
[HTML][HTML] Multifaceted Properties of Usnic Acid in Disrupting Cancer Hallmarks
M Gimła, A Herman-Antosiewicz - Biomedicines, 2024 - mdpi.com
Cancer, a complex group of diseases marked by uncontrolled cell growth and invasive
behavior, is characterized by distinct hallmarks acquired during tumor development. These …
behavior, is characterized by distinct hallmarks acquired during tumor development. These …